Journal article
Dosimetry for Radiopharmaceutical Therapy: Current Practices and Commercial Resources
The Journal of nuclear medicine (1978), Vol.62(Suppl 3), pp.3S-11S
12/2021
DOI: 10.2967/jnumed.121.262749
PMCID: PMC12079727
PMID: 34857621
Abstract
With the ongoing dramatic growth of radiopharmaceutical therapy, research and development in internal radiation dosimetry continue to advance both at academic medical centers and in industry. The basic paradigm for patient-specific dosimetry includes administration of a pretreatment tracer activity of the therapeutic radiopharmaceutical; measurement of its time-dependent biodistribution; definition of the pertinent anatomy; integration of the measured time-activity data to derive source-region time-integrated activities; calculation of the tumor, organ-at-risk, and/or whole-body absorbed doses; and prescription of the therapeutic administered activity. This paper provides an overview of the state of the art of patient-specific dosimetry for radiopharmaceutical therapy, including current methods and commercially available software and other resources.
Details
- Title: Subtitle
- Dosimetry for Radiopharmaceutical Therapy: Current Practices and Commercial Resources
- Creators
- Jacek Capala - National Cancer InstituteStephen A Graves - University of IowaAaron Scott - Johns Hopkins UniversityGeorge Sgouros - Johns Hopkins UniversitySara St James - University of California, San FranciscoPat Zanzonico - Memorial Sloan Kettering Cancer CenterBrian E Zimmerman - National Institute of Standards and Technology
- Resource Type
- Journal article
- Publication Details
- The Journal of nuclear medicine (1978), Vol.62(Suppl 3), pp.3S-11S
- DOI
- 10.2967/jnumed.121.262749
- PMID
- 34857621
- PMCID
- PMC12079727
- NLM abbreviation
- J Nucl Med
- ISSN
- 1535-5667
- eISSN
- 1535-5667
- Language
- English
- Date published
- 12/2021
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology; Radiation Oncology
- Record Identifier
- 9984383892002771
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