Journal article
Double-lumen central venous catheters impregnated with chlorhexidine and silver sulfadiazine to prevent catheter colonisation in the intensive care unit setting: a prospective randomised study
Journal of Hospital Infection, Vol.72(3), pp.227-233
2009
DOI: 10.1016/j.jhin.2009.03.018
PMID: 19443078
Abstract
Antimicrobial- and antiseptic-impregnated catheters are strategies recommended to prevent central venous catheter (CVC) colonisation. Few data regarding chlorhexidine/silver sulfadiazine-impregnated catheters in intensive care unit (ICU) patients have been reported. We performed a prospective, randomised study comparing the colonisation rates of chlorhexidine/silver sulfadiazine-impregnated CVCs (group 1) against standard CVCs (group 2). In order to assess catheter colonisation rates, a 4 cm segment from the tips of aseptically removed catheters was cultured by the roll-plate method. In all, 109 patients were enrolled with successful catheter insertion, 51 of them in group 1 and 58 in group 2. There were no statistically significant differences between the two groups with regards to age, Sequential Organ Failure Assessment (SOFA) score, ICU admission diagnosis, infection risk, catheter insertion sites or catheter length of stay. The colonisation rates were 29.4% (15 catheters) for group 1 and 34.5% (20 catheters) for group 2 ( P = 0.50). Double-lumen CVCs impregnated with chlorhexidine and silver sulfadiazine were not effective in reducing the incidence of catheter colonisation in ICU patients.
Details
- Title: Subtitle
- Double-lumen central venous catheters impregnated with chlorhexidine and silver sulfadiazine to prevent catheter colonisation in the intensive care unit setting: a prospective randomised study
- Creators
- L.F.A Camargo - Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo, BrazilA.R Marra - Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo, BrazilG.L Büchele - Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo, BrazilA.M.C Sogayar - Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo, BrazilR.G.R Cal - Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo, BrazilJ.M.A de Sousa - Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo, BrazilE Silva - Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo, BrazilE Knobel - Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo, BrazilM.B Edmond - Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA
- Resource Type
- Journal article
- Publication Details
- Journal of Hospital Infection, Vol.72(3), pp.227-233
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/j.jhin.2009.03.018
- PMID
- 19443078
- ISSN
- 0195-6701
- eISSN
- 1532-2939
- Language
- English
- Date published
- 2009
- Academic Unit
- Infectious Diseases; Internal Medicine
- Record Identifier
- 9983905533002771
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