Journal article
Drinking after osmotic challenge depends on circadian phase in rats with free-running rhythms
American journal of physiology. Regulatory, integrative and comparative physiology, Vol.261(2), pp.R334-R338
08/01/1991
DOI: 10.1152/ajpregu.1991.261.2.R334
PMID: 1877692
Abstract
Rhythmic phase-dependent modulation of the amount of water intake of rats occurs after several types of dipsogenic treatments. Previous studies conducted on rats in light-dark cycles confound direct effects of the light-dark cycle with the effects of circadian rhythmicity entrained to the light-dark cycle. The present study isolates the effect of circadian phase on the amount of drinking induced by injection of hypertonic saline. Free-running rhythms were induced in rats, and then water intake was measured after injections of both hypertonic and isotonic saline at different phases of the rats' circadian cycle. After injections of hypertonic saline, rats drank more water in their active phase than in their inactive phase. No difference in the amount of intake was found in rats that received isotonic saline at different phases of their circadian rhythms. The results indicate a circadian modulation of the drinking induced by cellular dehydration.
Details
- Title: Subtitle
- Drinking after osmotic challenge depends on circadian phase in rats with free-running rhythms
- Creators
- R. F Johnson - Department of Psychology, University of Iowa, Iowa City 52242A. K Johnson - Department of Psychology, University of Iowa, Iowa City 52242
- Resource Type
- Journal article
- Publication Details
- American journal of physiology. Regulatory, integrative and comparative physiology, Vol.261(2), pp.R334-R338
- DOI
- 10.1152/ajpregu.1991.261.2.R334
- PMID
- 1877692
- ISSN
- 0363-6119
- eISSN
- 1522-1490
- Language
- English
- Date published
- 08/01/1991
- Academic Unit
- Psychological and Brain Sciences; Neuroscience and Pharmacology; Health and Human Physiology
- Record Identifier
- 9984214756302771
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