Dural involvement in central nervous system langerhans cells histiocytosis (LCH) on FDG PET/CT: Case report and review of CNS manifestations of LCH on PET/CT

Assim Saad Eddin; Parren McNeely; Mothana Saad Eldine; Lillian Lai; Ahmad Shariftabrizi

doi:10.1016/j.radcr.2023.12.044

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Dural involvement in central nervous system langerhans cells histiocytosis (LCH) on FDG PET/CT: Case report and review of CNS manifestations of LCH on PET/CT

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Dural involvement in central nervous system langerhans cells histiocytosis (LCH) on FDG PET/CT: Case report and review of CNS manifestations of LCH on PET/CT

Assim Saad Eddin, Parren McNeely, Mothana Saad Eldine, Lillian Lai and Ahmad Shariftabrizi

Radiology case reports, Vol.19(4), pp.1391-1396

04/2024

DOI: 10.1016/j.radcr.2023.12.044

PMCID: PMC10803779

PMID: 38268737

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Abstract

We report a case of multisystem Langerhans cell histiocytosis in a pediatric patient with central nervous system involvement, highlighting F-18(FDG) uptake characteristics of dural sites of disease. We also highlight the advantages of functional data offered by FDG-PET as a useful follow-up tool to assess viability and, therefore, treatment response of previously known central nervous system lesions. The utility of recognizing characteristic patterns of FDG uptake in dural disease is also applicable in cases of diagnostic uncertainty, such as when evaluating isolated dural lesions or when distinguishing between Langerhans cell histiocytosis and similar appearing lesions such as meningiomas.

Details

Title: Subtitle: Dural involvement in central nervous system langerhans cells histiocytosis (LCH) on FDG PET/CT: Case report and review of CNS manifestations of LCH on PET/CT
Creators: Assim Saad Eddin - University of Iowa Hospitals and Clinics
Parren McNeely - University of Iowa
Mothana Saad Eldine
Lillian Lai
Ahmad Shariftabrizi - University of Iowa
Resource Type: Journal article
Publication Details: Radiology case reports, Vol.19(4), pp.1391-1396
DOI: 10.1016/j.radcr.2023.12.044
PMID: 38268737
PMCID: PMC10803779
NLM abbreviation: Radiol Case Rep
ISSN: 1930-0433
eISSN: 1930-0433
Language: English
Date published: 04/2024
Academic Unit: Radiology; Stead Family Department of Pediatrics
Record Identifier: 9984548410202771

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