Journal article
Dyadic Comparison of Pain and Stress in Alzheimer's Disease and Caregivers
Pain management nursing, Vol.26(2), pp.190-197
04/2025
DOI: 10.1016/j.pmn.2024.10.010
PMCID: PMC11957937
PMID: 39632151
Abstract
Millions of people live with dementia worldwide, relying heavily on family caregivers. Pain is common in both people living with Alzheimer's disease (PLWAD) and their caregivers, contributing to stress and burden. To our knowledge, this is the first study to examine the relationship between pain, stress, hair cortisol, and mental health in PLWAD and their caregivers and how these factors are linked to caregiver burden.
This exploratory pilot study included five PLWAD-caregiver dyads. Participants completed questionnaires on pain, mental health, and demographics. Hair samples were collected for cortisol analysis. Pearson correlation coefficients (r) were used to assess relationships between various factors of PLWAD and their caregivers.
Contrary to expectations, pain and mental health measures for PLWAD displayed a trend toward negative correlation with their hair cortisol levels. Conversely, caregiver pain and mental health measures had a trend toward positive correlation with their hair cortisol levels. There was also a trend that higher pain in PLWAD was associated with higher caregiver burden.
This exploratory pilot study showed associational trends suggesting a complex relationship between pain, mental health, and stress in PLWAD-caregiver dyads. This preliminary work will inform future studies that can help advance targeted, tailored interventions.
Details
- Title: Subtitle
- Dyadic Comparison of Pain and Stress in Alzheimer's Disease and Caregivers
- Creators
- Alison R AndersonJuliana Souza-TalaricoIshika MahajanTodd B MonroeAlai TanAmy R MackosJodi L FordKathy D WrightTanya GureKaren M RoseKaren O Moss
- Resource Type
- Journal article
- Publication Details
- Pain management nursing, Vol.26(2), pp.190-197
- DOI
- 10.1016/j.pmn.2024.10.010
- PMID
- 39632151
- PMCID
- PMC11957937
- NLM abbreviation
- Pain Manag Nurs
- ISSN
- 1524-9042
- eISSN
- 1532-8635
- Publisher
- ELSEVIER SCIENCE INC
- Grant note
- Ohio State University College of Nursing Research and Development FundsNational Center for Advancing Translational Sciences of the National Institutes of HealthNIH-NINRNIH-NIA: R01AG061325, 1R21AG077069-01 Harold Amos Medical Faculty Development Program from the Robert Wood Johnson Foundation
This study was supported by The Ohio State University College of Nursing Research and Development Funds awarded to Dr. Moss. This project was also supported, in part, by the National Center for Advancing Translational Sciences of the National Institutes of Health under Grant Number UL1TR002733. Dr. Ander-son was supported by NIH-NINR T32NR014225. Partial salary support was provided to Dr. Moss from NIH-NIA grant R01AG059861. Drs. Monroe and Rose were partly supported by NIH-NIA grants R01AG059861 and R01AG061325 . Dr. Wright was partly supported by a Harold Amos Medical Faculty Development Program from the Robert Wood Johnson Foundation and NIH-NIA 1R21AG077069-01. The content is solely the authors' responsibility and does not necessarily represent the official views of the National Institutes of Health.
- Language
- English
- Electronic publication date
- 12/03/2024
- Date published
- 04/2025
- Academic Unit
- Iowa Neuroscience Institute; Nursing
- Record Identifier
- 9984757066602771
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