Journal article
Dynamic Contrast-Enhanced (DCE) MRI
Magnetic resonance imaging clinics of North America, Vol.32(1), pp.47-61
02/2024
DOI: 10.1016/j.mric.2023.09.001
Abstract
The non-invasive dynamic contrast-enhanced MRI (DCE-MRI) method provides valuable insights into tissue perfusion and vascularity. Primarily used in oncology, DCE-MRI is typically utilized to assess morphology and contrast agent (CA) kinetics in the tissue of interest. Interpretation of the temporal signatures of DCE-MRI data includes qualitative, semi-quantitative, and quantitative approaches. Recent advances in MRI technology allow simultaneous high spatial and temporal resolutions in DCE-MRI data acquisition on most vendor platforms, enabling the more desirable approach of quantitative data analysis using pharmacokinetic (PK) modeling. Many technical factors, including signal-to-noise ratio, temporal resolution, quantifications of arterial input function and native tissue T1, and PK model selection, need to be carefully considered when performing quantitative DCE-MRI. Standardization in data acquisition and analysis is especially important in multi-center studies.
Details
- Title: Subtitle
- Dynamic Contrast-Enhanced (DCE) MRI
- Creators
- Xin Li - Oregon Health & Science UniversityWei Huang - Oregon Health & Science UniversityJames H. Holmes - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Magnetic resonance imaging clinics of North America, Vol.32(1), pp.47-61
- DOI
- 10.1016/j.mric.2023.09.001
- ISSN
- 1064-9689
- eISSN
- 1557-9786
- Grant note
- DOI: 10.13039/100000002, name: National Institutes of Health, award: R01 CA248192
- Language
- English
- Electronic publication date
- 10/2023
- Date published
- 02/2024
- Academic Unit
- Iowa Neuroscience Institute; Radiology; Roy J. Carver Department of Biomedical Engineering
- Record Identifier
- 9984474572002771
Metrics
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