Dynamic, Real-Time, Fiducial-Free Surgical Navigation with Integrated Multimodal Optical Imaging

Tri T Quang; Wei F Chen; Francis A Papay; Yang Liu

doi:10.1109/JPHOT.2020.3042269

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Dynamic, Real-Time, Fiducial-Free Surgical Navigation with Integrated Multimodal Optical Imaging

Journal article

Open access

Peer reviewed

Dynamic, Real-Time, Fiducial-Free Surgical Navigation with Integrated Multimodal Optical Imaging

Tri T Quang, Wei F Chen, Francis A Papay and Yang Liu

IEEE photonics journal, Vol.13(1), 3900113

02/2021

DOI: 10.1109/JPHOT.2020.3042269

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Abstract

Surgeons need surgical navigation and intraoperative imaging for accurate surgery. However, current clinical surgical navigation systems have many drawbacks, including the need of fiducial markers, the lack of real-time registration update, and lack of functional imaging. We have developed a novel Real-time Fluorescence Imaging Topography Scanning (RFITS) system that delivers simultaneous real-time multimodal optical imaging, CT-to-Optical image registration, and dynamic fiducial-free surgical navigation. The RFITS prototype was characterized to evaluate system performance and used in biological models for fluorescence-guided surgery. We also performed multimodal imaging of a casting life-sized human cranial model and investigated image registration between intraoperative optical image data and preoperative tomographic image data. The RFITS prototype successfully integrated real-time intraoperative optical imaging and dynamic CT-based surgical navigation, offering complementary functional and structural information for surgical guidance. Our results demonstrated that the RFITS system can provide accurate multimodal surgical guidance in preclinical studies. To the best of our knowledge, this is the first report of a system capable of concurrent intraoperative fluorescence imaging and dynamic, real-time, CT-based navigation, whereas multiple modalities are accurately registered.

Fluorescence

Navigation

Surgery

Biophotonics

fluorescence imaging

image-guided surgery

Imaging

infrared imaging

optical imaging

Prototypes

real-time

Real-time systems

Surfaces

surgical navigation

Details

Title: Subtitle: Dynamic, Real-Time, Fiducial-Free Surgical Navigation with Integrated Multimodal Optical Imaging
Creators: Tri T Quang - University of Iowa
Wei F Chen - Cleveland Clinic
Francis A Papay - Cleveland Clinic
Yang Liu - University of Iowa
Resource Type: Journal article
Publication Details: IEEE photonics journal, Vol.13(1), 3900113
Publisher: IEEE
DOI: 10.1109/JPHOT.2020.3042269
ISSN: 1943-0655
eISSN: 1943-0655
Grant note: ASLMS Student Research University of Iowa Startup Funds FA8650-16-2-6702 / U.S. Air Force (10.13039/100006831)
Language: English
Date published: 02/2021
Academic Unit: Electrical and Computer Engineering
Record Identifier: 9984197275202771

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