Journal article
Dynamics of intraoperative Klebsiella, Acinetobacter, Pseudomonas, and Enterobacter transmission
American journal of infection control, Vol.46(5), pp.526-532
05/2018
DOI: 10.1016/j.ajic.2017.10.018
PMID: 29395508
Abstract
•Acinetobacter spp are more likely to be isolated from anesthesia provider hands.•Enterobacter spp are more likely to be isolated from patient skin sites.•Klebsiella, Acinetobacter, Pseudomonas, and Enterobacter epidemiologically related transmission events often involve anesthesia provider hands.•Klebsiella, Acinetobacter, Pseudomonas, and Enterobacter pathogens are frequently transmitted between operating room environments.
Our primary objective was to examine anesthesia work area reservoir isolation of Klebsiella, Acinetobacter, Pseudomonas, and Enterobacter spp (KAPE) pathogens. This is a retrospective analysis of a randomized, prospective, and observational study involving 3 academic medical centers.
Patients included adults undergoing general anesthesia. Gram-negative isolates (N = 2,682) were collected from anesthesia work area reservoirs in 274 randomly selected operating room case pairs. Nine hundred and forty-five isolates were included in this study. Chi square tests were used to examine the association of anesthesia work area reservoirs with KAPE genera isolation.
Acinetobacter pathogens were more likely to be isolated from anesthesia provider hands (risk ratio [RR], 1.07; 95% confidence interval [CI], 1.04-1.10; corrected P = .004) and less likely to be isolated from patients (RR, 0.2; 95% CI, 0.08-0.50; corrected P < .0001). Enterobacter pathogens were more likely to be isolated from patients (RR, 3.34; 95% CI, 1.92-5.81; corrected P = 0.001) and less likely to be isolated from provider hands (RR, 0.89; 95% CI, 0.83-0.97; corrected P = .007).
Anesthesia provider hands are important reservoirs for Acinetobacter spp, whereas patient skin surfaces are key reservoirs for Enterobacter spp. Future work should examine the impact of a multimodal program in controlling the intraoperative spread of Acinetobacter and Enterobacter pathogens.
Details
- Title: Subtitle
- Dynamics of intraoperative Klebsiella, Acinetobacter, Pseudomonas, and Enterobacter transmission
- Creators
- Brent Hadder - Department of Anesthesiology, University of Iowa Hospitals and Clinics, Iowa, IAHetal M Patel - Department of Anesthesiology, Dartmouth-Hitchcock Medical Center, Lebanon, NHRandy W Loftus - Department of Anesthesiology, University of Iowa Hospitals and Clinics, Iowa, IA
- Resource Type
- Journal article
- Publication Details
- American journal of infection control, Vol.46(5), pp.526-532
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.ajic.2017.10.018
- PMID
- 29395508
- ISSN
- 0196-6553
- eISSN
- 1527-3296
- Grant note
- Dartmouth-Hitchcock Medical Center (https://doi.org/10.13039/100008325) The University of Iowa
- Language
- English
- Date published
- 05/2018
- Academic Unit
- Anesthesia
- Record Identifier
- 9984006464902771
Metrics
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