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Dynamics of the light-induced current in Hermissenda
Journal article   Peer reviewed

Dynamics of the light-induced current in Hermissenda

Neurocomputing (Amsterdam), Vol.26, pp.61-67
06/01/1999
DOI: 10.1016/S0925-2312(99)00007-7

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Abstract

Although many of the biochemical reactions involved in phototransduction have been characterized, the identity of the ligand of the light-induced current is still unknown. The present study addresses the issue of which ligand activates the light-induced sodium current in Hermissenda by developing a model of the biochemical reactions involved in phototransduction, and examining the dynamics of the light-induced current in response to various ligands such as calcium and IP 3. The results show that IP 3, but not calcium, is a plausible ligand for the light-induced sodium current, and IP 3 production is co-localized with the sodium channel.
Calcium release Computer model Invertebrate Phototransduction Sodium current

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