Logo image
IRO Home Research units Researcher Profiles
Sign in
Dystrophin-glycoprotein complex: molecular organization and critical roles in skeletal muscle
Journal article   Peer reviewed

Dystrophin-glycoprotein complex: molecular organization and critical roles in skeletal muscle

Yoshihide Sunada and Kevin P Campbell
Current opinion in neurology, Vol.8(5), pp.379-384
10/1995
DOI: 10.1097/00019052-199510000-00010
PMID: 8542044

View Online

Abstract

Recent molecular and biochemical studies have disclosed the detailed molecular organization of the dystrophin-glycoprotein complex, which links the cytoskeleton to the extracellular matrix. Defects in several components of this complex cause different types of muscular dystrophy. This glycoprotein complex is also involved in clustering and anchoring acetylcholine receptors at the postsynaptic membrane.

Details

Metrics

Logo image