Journal article
EFFECTS OF CYTOSINE-ARABINOSIDE ON UNSEPARATED BONE-MARROW AND PERIPHERAL-BLOOD CELLS AND ON SPECIMENS ENRICHED FOR MYELOBLASTS AND PROMYELOCYTES
Experimental hematology, Vol.8(4), pp.404-408
01/01/1980
PMID: 7461048
Abstract
Myeloblast and promyelocyte enriched preparations and the original unseparated specimens were compared in regard to the phosphorylation of cytosine arabinoside (ara C) and the retention of ara CTP as well as the effects of ara C on the clonogenic cells. The immature cell-enriched preparations have a significantly higher rate of ara C phosphorylation, while retention of ara CTP is not significantly different from that of the unseparated cells. No correlation was found between the measured parameters of ara C metabolism and the drug's effects on the clonogenic cells in either cell population.
Details
- Title: Subtitle
- EFFECTS OF CYTOSINE-ARABINOSIDE ON UNSEPARATED BONE-MARROW AND PERIPHERAL-BLOOD CELLS AND ON SPECIMENS ENRICHED FOR MYELOBLASTS AND PROMYELOCYTES
- Creators
- J EpsteinH D PreislerY M RustumD J Higby
- Resource Type
- Journal article
- Publication Details
- Experimental hematology, Vol.8(4), pp.404-408
- Publisher
- CARDEN JENNINGS PUBL CO LTD
- PMID
- 7461048
- ISSN
- 0301-472X
- eISSN
- 1873-2399
- Number of pages
- 5
- Grant note
- P01CA021071 / NATIONAL CANCER INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI) CA-21071; CA-17785; CA-5834 / NCI NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI)
- Language
- English
- Date published
- 01/01/1980
- Academic Unit
- Hematology, Oncology, and Blood & Marrow Transplantation; Internal Medicine
- Record Identifier
- 9984360057202771
Metrics
13 Record Views