EFFECTS OF DECOMPRESSION TIME AFTER SPINAL CORD INJURY ON NEUROLOGIC RECOVERY IN WISTAR RATS

Cesar de Cesar Netto; Leonardo Franco Pinheiro Gaia; Alexandre Adorno Sattin; Alexandre Fogaca Cristante; Raphael Martus Marcon; Tarcisio Eloy Pessoa de Barros Filho; Reginaldo Perilo Oliveira; Ivan Dias Rocha; Arthur Roncon Dias; Clarissa Harumi Omori

doi:10.1590/S1413-78522010000600002

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EFFECTS OF DECOMPRESSION TIME AFTER SPINAL CORD INJURY ON NEUROLOGIC RECOVERY IN WISTAR RATS

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EFFECTS OF DECOMPRESSION TIME AFTER SPINAL CORD INJURY ON NEUROLOGIC RECOVERY IN WISTAR RATS

Cesar de Cesar Netto, Leonardo Franco Pinheiro Gaia, Alexandre Adorno Sattin, Alexandre Fogaca Cristante, Raphael Martus Marcon, Tarcisio Eloy Pessoa de Barros Filho, Reginaldo Perilo Oliveira, Ivan Dias Rocha, Arthur Roncon Dias and Clarissa Harumi Omori

Acta ortopedica brasileira, Vol.18(6), pp.315-320

01/01/2010

DOI: 10.1590/S1413-78522010000600002

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Abstract

Objective Traumatic spinal Cord injuries are common in patients with high energy trauma and have significant morbidity and mortality rates as well as high psychological and social costs causing a major impact on public health To date the treatment of such lesions remains controversial with various studies in the literature comparing the results of non surgical treatment with immediate early or late surgical decompression The objective of the present study is to compare the results of immediate and early (within 1 hour) spinal Cord decompression Methods In the belief that the surgical treatment obtains the best result this experimental study has a case control design with histopathological and functional analysis of the results of surgical treatment of 25 Wistar mice submitted to posterior laminectomy immediately or after one hour of spinal Cord compression Results in terms of functional and neurological deficit the responses were better in the mice treated with immediate surgical decompression than in those treated one hour after the lesion (p=0 036) Conclusion The earlier the decompression of spinal Cord injuries is performed the better the end results in terms of the function and presence of neurological deficit

Life Sciences & Biomedicine

Orthopedics

Science & Technology

Details

Title: Subtitle: EFFECTS OF DECOMPRESSION TIME AFTER SPINAL CORD INJURY ON NEUROLOGIC RECOVERY IN WISTAR RATS
Creators: Cesar de Cesar Netto - FMUSP, Dept Orthoped & Traumatol, Lab Med Invest Musculoskeletal Syst LIM41, Sao Paulo, Brazil
Leonardo Franco Pinheiro Gaia - FMUSP, Dept Orthoped & Traumatol, Lab Med Invest Musculoskeletal Syst LIM41, Sao Paulo, Brazil
Alexandre Adorno Sattin - FMUSP
Alexandre Fogaca Cristante - FMUSP
Raphael Martus Marcon - FMUSP
Tarcisio Eloy Pessoa de Barros Filho - FMUSP, Dept Orthoped & Traumatol, Lab Med Invest Musculoskeletal Syst LIM41, Sao Paulo, Brazil
Reginaldo Perilo Oliveira - FMUSP
Ivan Dias Rocha - FMUSP, Dept Orthoped & Traumatol, Lab Med Invest Musculoskeletal Syst LIM41, Sao Paulo, Brazil
Arthur Roncon Dias - FMUSP
Clarissa Harumi Omori - Univ Sao Paulo, Sch Med, BR-05508 Sao Paulo, Brazil
Resource Type: Journal article
Publication Details: Acta ortopedica brasileira, Vol.18(6), pp.315-320
DOI: 10.1590/S1413-78522010000600002
ISSN: 1413-7852
eISSN: 1809-4406
Publisher: Atha Comunicacao & Editora
Number of pages: 6
Language: English
Date published: 01/01/2010
Academic Unit: Orthopedics and Rehabilitation
Record Identifier: 9984304722502771

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