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EFFECTS OF MUTANT DROSOPHILA K+ CHANNEL SUBUNITS ON HABITUATION OF THE OLFACTORY JUMP RESPONSE
Journal article   Peer reviewed

EFFECTS OF MUTANT DROSOPHILA K+ CHANNEL SUBUNITS ON HABITUATION OF THE OLFACTORY JUMP RESPONSE

M. A JOINER, Z ASZTALOS, C. J JONES, T TULLY and C.-F WU
Journal of neurogenetics, Vol.21(1-2), pp.45-58
2007
DOI: 10.1080/01677060701247375
PMCID: PMC3045562
PMID: 17464797
url
https://www.ncbi.nlm.nih.gov/pmc/articles/3045562View
Open Access

Abstract

The olfactory-jump response assay was used to analyze habituation in Drosophila mutants of potassium (K + ) channel subunits. As with physiological assays of the giant fiber-mediated escape reflex, mutations at loci that encode K + channel subunits have distinct effects on habituating the olfactory-jump response. The data for slowpoke and ether à go-go indicate similar effects on habituation of the olfactory-jump response and the giant fiber-mediated escape. Habituation in the olfactory jump assay in Hyperkinetic and Shaker mutants was drastically different from the degree of defect in the giant fiber-mediated escape reflex, indicating differential control mechanisms underlying the two forms of non-associative conditioning.
Invertebrate learning Escape reflex Hk Shab and Sh mutants Slo eag Giant fiber pathway Non-associative conditioning

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