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ERP indices of performance monitoring and feedback processing in psychosis: A meta-analysis
Journal article   Peer reviewed

ERP indices of performance monitoring and feedback processing in psychosis: A meta-analysis

Elizabeth A Martin, Amanda McCleery, Melody M Moore, Jonathan K Wynn, Michael F Green and William P Horan
International journal of psychophysiology, Vol.132(Pt B), pp.365-378
10/2018
DOI: 10.1016/j.ijpsycho.2018.08.004
PMCID: PMC6157731
PMID: 30102934

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Abstract

Although individuals with, or at risk for, psychotic disorders often show difficulties with performance monitoring and feedback processing, findings from studies using event-related potentials (ERPs) to index these processes are not consistent. This meta-analytic review focused on studies of two different indexes of performance monitoring, the early error-related negativity (ERN; n = 25) and the later error positivity (Pe; n = 17), and one index of feedback processing, the feedback negativity (FN; n = 6). We evaluated whether individuals (1) with psychotic disorders, or (2) at heightened risk for these disorders differ from healthy controls in available studies of the ERN, Pe, and FN. There was a significant, large ERN reduction in those with psychosis (g = −0.96) compared to controls, and a significant, moderate ERN reduction in those at-risk (g = −0.48). In contrast, there were uniformly non-significant, small between-group differences for Pe and FN (gs ≤ |0.16|). The results reveal a differential pattern of impairment in psychosis. Early performance monitoring (ERN) impairments are substantial among those with psychotic disorders in general and may be a useful vulnerability indicator for these disorders. However, later performance monitoring (Pe) and basic feedback processing (FN) appear to be relatively spared in psychosis. •There were moderate to large ERN reductions in psychosis and psychosis-risk.•There were non-significant, small differences from controls for Pe and FN.•Early responding monitoring is impaired in psychosis/psychosis-risk.•Later responding monitoring appears relatively intact across groups.•External feedback processing also appears to be relatively intact.
ERN Feedback-related negativity Error positivity Error-related negativity

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