EUS-guided through-the-needle biopsy for pancreatic cystic lesions

Jason Samarasena; Allen Yu; David Lee; Rintaro Hashimoto; Yuxin Lu; Daniel Thieu; Daniel Mai; John Lee; Kenneth Chang

doi:10.1016/j.vgie.2019.04.020

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EUS-guided through-the-needle biopsy for pancreatic cystic lesions

Journal article

Open access

Peer reviewed

EUS-guided through-the-needle biopsy for pancreatic cystic lesions

Jason Samarasena, Allen Yu, David Lee, Rintaro Hashimoto, Yuxin Lu, Daniel Thieu, Daniel Mai, John Lee and Kenneth Chang

VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy, Vol.4(9), pp.436-439

09/01/2019

DOI: 10.1016/j.vgie.2019.04.020

PMCID: PMC6731357

PMID: 31517173

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Abstract

Differentiating pancreatic cystic lesions remains a challenge when the current technique of EUS-guided FNA is used. Recently, a miniaturized biopsy forceps with an outer diameter of 0.8 mm has been developed, thus allowing it to be passed through the bore of a standard 19-gauge FNA needle to acquire tissue. This study consisted of a retrospective review of all cases of EUS-guided through-the-needle forceps biopsy technique (TTNFB) performed for pancreatic cystic lesions at a single academic tertiary care center over a 12-month period. Technical success was defined as acquisition of adequate tissue for formal histologic analysis. Safety was assessed through the monitoring and recording of periprocedural and postprocedural adverse events. The technical success of EUS-guided TTNFB was 87% (13/15). EUS-guided TTNFB with histologic analysis yielded pancreatic cyst diagnoses in 11 of 15 (73%) patients, compared with 0 of 15 (0%) patients with the use of EUS-FNA and cytologic analysis ( < .001). Of the 15 cystic lesions, 8 were diagnosed as intrapapillary mucinous neoplasm based on EUS-TTNFB. This TTNFB technique has the potential to improve the diagnostic yield of EUS-FNA for pancreatic cystic neoplasms.

MCN, mucinous cystic neoplasm

IPMN, intrapapillary mucinous neoplasm

TTNFB, through-the-needle forceps biopsy technique

Details

Title: Subtitle: EUS-guided through-the-needle biopsy for pancreatic cystic lesions
Creators: Jason Samarasena - University of California, Irvine
Allen Yu - University of California, Irvine
David Lee - University of California, Irvine
Rintaro Hashimoto - University of California, Irvine
Yuxin Lu - University of California, Irvine
Daniel Thieu - University of California, Irvine
Daniel Mai - University of California, Irvine
John Lee - University of California, Irvine
Kenneth Chang - University of California, Irvine
Resource Type: Journal article
Publication Details: VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy, Vol.4(9), pp.436-439
DOI: 10.1016/j.vgie.2019.04.020
PMID: 31517173
PMCID: PMC6731357
ISSN: 2468-4481
eISSN: 2468-4481
Language: English
Date published: 09/01/2019
Academic Unit: Internal Medicine
Record Identifier: 9984695835802771

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