Journal article
Early Outcomes of Tricuspid Valve Replacement in Young Children
Circulation (New York, N.Y.), Vol.115(3), pp.319-325
01/23/2007
DOI: 10.1161/CIRCULATIONAHA.106.618652
PMID: 17200445
Abstract
Background—
Early outcomes after tricuspid valve replacement in young children are ill defined. The experience of the Pediatric Cardiac Care Consortium (45 centers, 1984 to 2002) was reviewed to evaluate the results of tricuspid valve replacement in children <6 years of age.
Methods and Results—
Ninety-seven patients who underwent initial tricuspid valve replacement are included in the present analysis. The most frequent cardiac diagnoses were Ebstein’s anomaly (40%), pulmonary atresia (11%), and tetralogy of Fallot (8%). Age at tricuspid valve replacement was 2.9±1.7 years (mean±SD). Mean patient weight was 12.7±6.1 kg. The major outcome was survival to discharge. Associations among age, diagnosis, valve type/size, and outcome were evaluated through the use of χ
2
analysis and logistic regression model fitting approaches. Hospital mortality was 26% and was very high (64%) in patients <1 year of age. A large size-to-weight ratio was the strongest predictor of mortality based on multivariable analysis (
P
<0.001). Mortality was 54% for patients with a size-to-weight ratio >2.5. Other complications included heart block requiring a pacemaker (13%) and thrombosis (5%). Pacemaker implantation was associated with the use of a mechanical valve (23% versus 6% bioprosthetic valve;
P
=0.01)
Conclusions—
Tricuspid valve replacement in young children is associated with high mortality, especially in infants <1 year of age. Surgical options other than tricuspid valve replacement such as transplantation may need to be considered in infants.
Details
- Title: Subtitle
- Early Outcomes of Tricuspid Valve Replacement in Young Children
- Creators
- Heather L. Bartlett - Roy J. and Lucille A. Carver College of MedicineDianne L. Atkins - University of IowaTrudy L. Burns - University of IowaKelly J. Engelkes - University of IowaSarah J. PowellChristine B. Hills - University of Minnesota‐Twin CitiesJames H. Moller - Pediatrics - Pediatric Cardiology
- Resource Type
- Journal article
- Publication Details
- Circulation (New York, N.Y.), Vol.115(3), pp.319-325
- DOI
- 10.1161/CIRCULATIONAHA.106.618652
- PMID
- 17200445
- ISSN
- 0009-7322
- eISSN
- 1524-4539
- Language
- English
- Date published
- 01/23/2007
- Academic Unit
- Stead Family Department of Pediatrics; Epidemiology; Fraternal Order of Eagles Diabetes Research Center
- Record Identifier
- 9984364451502771
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