Journal article
Early Stage Relapsing Polychondritis Diagnosed by Nasal Septum Biopsy
Case reports in medicine, Vol.2015, pp.307868-4
01/01/2015
DOI: 10.1155/2015/307868
PMCID: PMC4710948
PMID: 26843866
Abstract
Relapsing polychondritis is a rare inflammation of cartilaginous tissues, the diagnosis of which is usually delayed by a mean period of 2.9 years from symptom onset. We present the case of a 36-year-old man with nasal pain and fever. Physical examination of the nose was grossly unremarkable, but there was significant tenderness of the nasal bridge. Acute sinusitis was initially diagnosed due to thickened left frontal sinus mucosa on computed tomography (CT); however, there was no improvement after antibiotic intake. Repeat CT showed edematous inflammation of the nasal septum; biopsy of this site demonstrated erosion and infiltration of lymphocytes, plasma cells, eosinophils, and neutrophils in the hyaline cartilage. Relapsing polychondritis was confirmed by the modifiedMcAdam's criteria and can be diagnosed at an early stage by nasal septum biopsy; it should be considered as a differential diagnosis in patients presenting with nasal symptoms alone or persistent sinus symptoms.
Details
- Title: Subtitle
- Early Stage Relapsing Polychondritis Diagnosed by Nasal Septum Biopsy
- Creators
- Takaaki Kobayashi - Mount Sinai Beth IsraelSandra Moody - University of California, San FranciscoMasafumi Komori - Kameda Medical CenterAkira Jibatake - Kameda Medical CenterMakito Yaegashi - Kameda Medical Center
- Resource Type
- Journal article
- Publication Details
- Case reports in medicine, Vol.2015, pp.307868-4
- DOI
- 10.1155/2015/307868
- PMID
- 26843866
- PMCID
- PMC4710948
- NLM abbreviation
- Case Rep Med
- ISSN
- 1687-9627
- eISSN
- 1687-9635
- Publisher
- Hindawi Publishing Group
- Number of pages
- 4
- Language
- English
- Date published
- 01/01/2015
- Academic Unit
- Infectious Diseases; Internal Medicine
- Record Identifier
- 9984362291102771
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