Journal article
Early medical risks to language development in extremely preterm infants
Journal of perinatology, Vol.45(3), pp.378-385
03/2025
DOI: 10.1038/s41372-024-02191-z
PMID: 39672899
Abstract
To study the mechanistic role of neonatal morbidities on language performance in extremely preterm (EP) infants.
We conducted secondary analyses on EP infants born at a single tertiary care center, investigating whether neonatal morbidities mediated associations between gestational age and language performance at 18-26 months corrected age.
Infants born at 25-26 weeks (n = 298) outperformed those born at 22-24 weeks (n = 177) in expressive communication, receptive communication, composite language, and cognition. Retinopathy of prematurity (ROP), grade 2/3 bronchopulmonary dysplasia (BPD), and cognition partially explained gestational age effects on expressive and receptive communication. In the final sequential path models, infants born 22-24 weeks gestation were more likely to be diagnosed with grade 2/3 BPD, which was linked to diminished cognitive skills, and reduced language skills.
Families of EP infants born under 25 weeks or with ROP and/or grade 2/3 BPD should be counseled about higher language impairment risk and receive proactive intervention.
Details
- Title: Subtitle
- Early medical risks to language development in extremely preterm infants
- Creators
- Paige M Nelson - University of IowaFrancesca Scheiber - University of IowaÖ Ece Demir-Lira - University of IowaHeidi M Harmon - Stead Family Department of Pediatrics, University of Iowa, Iowa City, IA, USA
- Resource Type
- Journal article
- Publication Details
- Journal of perinatology, Vol.45(3), pp.378-385
- DOI
- 10.1038/s41372-024-02191-z
- PMID
- 39672899
- NLM abbreviation
- J Perinatol
- ISSN
- 0743-8346
- eISSN
- 1476-5543
- Publisher
- Springer Nature
- Grant note
- T32GM108540 / U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) UG1HD053109 / U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- Language
- English
- Electronic publication date
- 12/13/2024
- Date published
- 03/2025
- Academic Unit
- Psychiatry; Stead Family Department of Pediatrics; Psychological and Brain Sciences; Iowa Neuroscience Institute; Center for Social Science Innovation; Neonatology
- Record Identifier
- 9984757269302771
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