Journal article
Early school outcomes for extremely preterm infants with transient neurological abnormalities
Developmental medicine and child neurology, Vol.57(9), pp.865-871
09/2015
DOI: 10.1111/dmcn.12811
PMCID: PMC4529817
PMID: 26014665
Abstract
Aim: To determine if transient neurological abnormalities (TNA) at 9 months corrected age predict cognitive, behavioral, and motor outcomes at 6 years of age in extremely preterm infants.
Method: A cohort of 124 extremely preterm infants (mean gestational age 25.5wks; 55 males, 69 females), admitted to our unit between 2001 and 2003, were classified based on the Amiel-Tison Neurological Assessment at 9 months and 20 months corrected age as having TNA (n=17), normal neurological assessment (n=89), or neurologically abnormal assessment (n=18). The children were assessed at a mean age of 5 years 11 months (SD 4mo) on cognition, academic achievement, motor ability, and behavior.
Results: Compared with children with a normal neurological assessment, children with TNA had higher postnatal exposure to steroids (35% vs 9%) and lower adjusted mean scores on spatial relations (84 [standard error {SE} 5] vs 98 [SE 2]), visual matching (79 [SE 5] vs 91 [SE 2]), letter-word identification (97 [SE 4] vs 108 [SE 1]), and spelling (76 [SE 4] vs 96 [SE 2]) (all p<0.05).
Interpretation: Despite a normalized neurological assessment, extremely preterm children with a history TNA are at higher risk for lower cognitive and academic skills than those with normal neurological findings during their first year of school.
Details
- Title: Subtitle
- Early school outcomes for extremely preterm infants with transient neurological abnormalities
- Creators
- Heidi M Harmon - Department of Pediatrics; Rainbow Babies and Children's Hospital; Case Western Reserve University; Cleveland OH USAH Gerry Taylor - Department of Pediatrics; Rainbow Babies and Children's Hospital; Case Western Reserve University; Cleveland OH USANori Minich - Department of Pediatrics; Rainbow Babies and Children's Hospital; Case Western Reserve University; Cleveland OH USADeanne Wilson-Costello - Department of Pediatrics; Rainbow Babies and Children's Hospital; Case Western Reserve University; Cleveland OH USAMaureen Hack - Department of Pediatrics; Rainbow Babies and Children's Hospital; Case Western Reserve University; Cleveland OH USA
- Resource Type
- Journal article
- Publication Details
- Developmental medicine and child neurology, Vol.57(9), pp.865-871
- DOI
- 10.1111/dmcn.12811
- PMID
- 26014665
- PMCID
- PMC4529817
- NLM abbreviation
- Dev Med Child Neurol
- ISSN
- 0012-1622
- eISSN
- 1469-8749
- Grant note
- DOI: 10.13039/100000002, name: National Institutes of Health, award: HD050309; DOI: 10.13039/100000002, name: National Institutes of Health, award: 5T32HD060537
- Language
- English
- Date published
- 09/2015
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology
- Record Identifier
- 9984093211402771
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