Journal article
Ebola Virus Entry into Host Cells: Identifying Therapeutic Strategies
Current clinical microbiology reports, Vol.2(3), pp.115-124
09/2015
DOI: 10.1007/s40588-015-0021-3
PMCID: PMC4617201
PMID: 26509109
Abstract
Filoviruses cause severe hemorrhagic fever in humans. The archetypal virus of this group, Ebola virus, is responsible for the current filovirus epidemic in West Africa. Filoviruses infect most mammalian cells, resulting in broad species tropism and likely contributing to rapid spread of virus throughout the body. A thorough understanding of filovirus entry events will facilitate the development of therapeutics against these critical steps in the viral life cycle. This review summarizes the current understanding of filovirus entry and discusses some of the recent advancements in therapeutic strategies that target entry.
Details
- Title: Subtitle
- Ebola Virus Entry into Host Cells: Identifying Therapeutic Strategies
- Creators
- Bethany Rhein - grid.214572.7 0000000419368294 Department of Microbiology University of Iowa 3-701 Bowen Science Building, 51 Newton Rd Iowa City IA 52242 USAWendy Maury - grid.214572.7 0000000419368294 Department of Microbiology University of Iowa 3-701 Bowen Science Building, 51 Newton Rd Iowa City IA 52242 USA
- Resource Type
- Journal article
- Publication Details
- Current clinical microbiology reports, Vol.2(3), pp.115-124
- Publisher
- Springer International Publishing
- DOI
- 10.1007/s40588-015-0021-3
- PMID
- 26509109
- PMCID
- PMC4617201
- ISSN
- 2196-5471
- eISSN
- 2196-5471
- Language
- English
- Date published
- 09/2015
- Academic Unit
- Microbiology and Immunology
- Record Identifier
- 9984083265702771
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