Journal article
Effect of Bioactive Primers on Bacterial-Induced Secondary Caries at the Tooth-Resin Interface
Operative dentistry, Vol.42(2), pp.196-202
11/28/2016
DOI: 10.2341/16-107-L
PMCID: PMC5976884
PMID: 27892838
Abstract
Secondary caries at the tooth-resin interface is the primary reason for replacement of resin composite restorations. The tooth-resin interface is formed by the interlocking of resin material with hydroxyapatite crystals in enamel and collagen mesh structure in dentin. Efforts to strengthen the tooth-resin interface have identified chemical agents with dentin collagen cross-linking potential and antimicrobial activities. The purpose of the present study was to assess protective effects of bioactive primer against secondary caries development around enamel and dentin margins of class V restorations, using an in vitro bacterial caries model. Class V composite restorations were prepared on 60 bovine teeth (n=15) with pretreatment of the cavity walls with control buffer solution, an enriched fraction of grape seed extract (e-GSE), 1-ethyl-3-(3-dimethyl aminopropyl)-carbodiimide/
N
-hydroxysuccinimide, or chlorhexidine digluconate. After incubating specimens in a bacterial model with
Streptococcus mutans
for four days, dentin and enamel were assessed by fluorescence microscopy. Results revealed that only the naturally occurring product, e-GSE, significantly inhibited the development of secondary caries immediately adjacent to the dentin-resin interface, as indicated by the caries inhibition zone. No inhibitory effects were observed in enamel margins. The results suggest that the incorporation of e-GSE into components of the adhesive system may inhibit secondary caries and potentially contribute to the protection of highly vulnerable dentin-resin margins.
Details
- Title: Subtitle
- Effect of Bioactive Primers on Bacterial-Induced Secondary Caries at the Tooth-Resin Interface
- Creators
- Go Eun Kim - University of Illinois ChicagoAriene Arcas Leme-Kraus - University of Illinois ChicagoRasika Phansalkar - University of Illinois ChicagoGrace Viana - University of Illinois ChicagoChristine Wu - University of Illinois ChicagoShao-Nong Chen - University of Illinois ChicagoGuido Frank Pauli - University of Illinois ChicagoAna Karina Barbieri Bedran-Russo - University of Illinois Chicago
- Resource Type
- Journal article
- Publication Details
- Operative dentistry, Vol.42(2), pp.196-202
- DOI
- 10.2341/16-107-L
- PMID
- 27892838
- PMCID
- PMC5976884
- NLM abbreviation
- Oper Dent
- ISSN
- 0361-7734
- eISSN
- 1559-2863
- Language
- English
- Date published
- 11/28/2016
- Academic Unit
- Operative Dentistry
- Record Identifier
- 9984367651102771
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