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Effect of GB virus C viremia on HIV acquisition and HIV set-point
Journal article   Open access   Peer reviewed

Effect of GB virus C viremia on HIV acquisition and HIV set-point

Gregory P BISSON, Brian L STROM, Robert GROSS, Drew WEISSMAN, Donna KLINZMAN, Wei-Ting HWANG, Jay R KOSTMAN, David METZGER, Jack T STAPLETON and Ian FRANK
AIDS (London), Vol.19(16), pp.1910-1912
2005
DOI: 10.1097/01.aids.0000188427.25657.e7
PMID: 16227800
url
https://doi.org/10.1097/01.aids.0000188427.25657.e7View
Published (Version of record) Open Access

Abstract

We performed both a case–control study and a cohort study to determine whether GB virus C (GBV-C) viremia prevents the acquisition of HIV infection or alters the HIV set-point after infection. The prevalence of GBV-C viremia in HIV-uninfected individuals who did and did not acquire HIV were similar (odds ratio 1.32; 95% confidence interval 0.6–2.6). Pre-existing GBV-C viremia at the time of HIV acquisition was also not associated with lower plasma HIV-RNA levels.
Immunopathology Infectious Diseases Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Biological and medical sciences Medical sciences Human viral diseases Immunodeficiencies. Immunoglobulinopathies Immunodeficiencies

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