Journal article
Effect of Root Canal Filling/Sealer Systems on Apical Endotoxin Penetration: A Coronal Leakage Evaluation
Journal of endodontics, Vol.31(8), pp.599-604
2005
DOI: 10.1097/01.don.0000153843.25887.69
PMID: 16044044
Abstract
Endotoxin, elaborated by gram-negative organisms, is an important factor in apical periodontitis. The objective of this study was to evaluate the magnitude of endotoxin penetration through root canal treated teeth using a dual chamber model system. Forty-four maxillary anterior teeth were prepared endodontically and canals filled either by lateral condensation or a warm thermoplasticized technique in combination with either Roth's 801 or AH 26 sealer. Teeth were suspended in the model system with a mixed anaerobic bacterial suspension in the upper chamber and HBSS in the lower chamber. The QCL-1000 LAL assay was used to measure endotoxin at 0, 1, 7, 14, and 21 days. Response feature analysis using trapezoidal area under the curve was performed; the four treatment groups were compared using nonparametric methods. Groups differed (p = 0.028), with thermoplasticized root canal filling/Roth's 801 sealer permitting the least apical endotoxin penetration. Results suggest that Roth's 801 sealer may have a role in inhibiting endotoxin penetration.
Details
- Title: Subtitle
- Effect of Root Canal Filling/Sealer Systems on Apical Endotoxin Penetration: A Coronal Leakage Evaluation
- Creators
- Anne E WilliamsonDeborah V DawsonDavid R DrakeRichard E WaltonEric M Rivera
- Resource Type
- Journal article
- Publication Details
- Journal of endodontics, Vol.31(8), pp.599-604
- DOI
- 10.1097/01.don.0000153843.25887.69
- PMID
- 16044044
- NLM abbreviation
- J Endod
- ISSN
- 0099-2399
- eISSN
- 1878-3554
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 2005
- Academic Unit
- Endodontics; Biostatistics; Pediatric Dentistry; Family Dentistry; Dental Research
- Record Identifier
- 9984066077302771
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