Journal article
Effect of TAVR Approach and Other Baseline Factors on the Incidence of Acute Kidney Injury: A Systematic Review and Meta-Analysis
Journal of interventional cardiology, Vol.2022, pp.1-9
10/27/2022
DOI: 10.1155/2022/3380605
PMCID: PMC9633203
PMID: 36348992
Abstract
Background. Acute kidney injury (AKI) is a well-known complication following a transcatheter aortic valve replacement (TAVR) and is associated with higher morbidity and mortality. Objective. We aim to compare the risk of developing AKI after transfemoral (TF), transapical (TA), and transaortic (TAo) approaches following TAVR. Methods. We searched Medline and EMBASE databases from January 2009 to January 2021. We included studies that evaluated the risk of AKI based on different TAVR approaches. After extracting each study’s data, we calculated the risk ratio and 95% confidence intervals using RevMan software 5.4. Publication bias was assessed by the forest plot. Results. Thirty-six (36) studies, consisting of 70,406 patients undergoing TAVR were included. Thirty-five studies compared TF to TA, and only seven investigations compared TF to TAo. AKI was documented in 4,857 out of 50,395 (9.6%) patients that underwent TF TAVR compared to 3,155 out of 19,721 (16%) patients who underwent TA-TAVR, with a risk ratio of 0.49 (95% CI, 0.36–0.66;
p
<
0.00001
). Likewise, 273 patients developed AKI out of the 1,840 patients (14.8%) that underwent TF-TAVR in contrast to 67 patients out of the 421 patients (15.9%) that underwent TAo-TAVR, with a risk ratio of 0.51 (95% CI, 0.27–0.98; p = 0.04). There was no significant risk when we compared TA to TAo approaches, with a risk ratio of 0.89 (95% CI, 0.29–2.75; p = 0.84). Conclusion. The risk of post-TAVR AKI is significantly lower in patients who underwent TF-TAVR than those who underwent TA-TAVR or TAo-TAVR.
Details
- Title: Subtitle
- Effect of TAVR Approach and Other Baseline Factors on the Incidence of Acute Kidney Injury: A Systematic Review and Meta-Analysis
- Creators
- Hossam Alzu’bi - Mayo Clinic in ArizonaAnan Abu Rmilah - University of Iowa, Internal MedicineIkram-UI Haq - Mayo Clinic in ArizonaBabikir Kheiri - Oregon Health & Science UniversityAhmad Al-abdouh - Saint Agnes HospitalBashar Hasan - Mayo Clinic in FloridaOmar Elsekaily - Mayo Clinic in ArizonaSuhaib Jaber - Department of Internal Medicine, Dr. Sulaiman Al Habib Hospital, Riyadh, Saudi ArabiaIbraheem Qaisi - An-Najah National UniversityAsil Yagmour - Al-Quds UniversityHamada Dajani - An-Najah National UniversityAzza Ahmed - Mayo Clinic in ArizonaAhmed elhag - Department of Internal Medicine, Dr. Sulaiman Al Habib Hospital, Riyadh, Saudi ArabiaKianoush Kashani - Mayo ClinicAbhishek Deshmukh - Mayo Clinic in Arizona
- Resource Type
- Journal article
- Publication Details
- Journal of interventional cardiology, Vol.2022, pp.1-9
- DOI
- 10.1155/2022/3380605
- PMID
- 36348992
- PMCID
- PMC9633203
- NLM abbreviation
- J Interv Cardiol
- ISSN
- 0896-4327
- eISSN
- 1540-8183
- Number of pages
- 9
- Language
- English
- Date published
- 10/27/2022
- Academic Unit
- Internal Medicine
- Record Identifier
- 9984845252802771
Metrics
1 Record Views