Journal article
Effect of acidosis and hypoxia on intestinal blood flow of sheep fetus
Biology of the neonate, Vol.49(1), pp.29-35
1986
DOI: 10.1159/000242506
PMID: 3947690
Abstract
In sheep fetuses 110–130 days of age acidosis (blood pH 6.95; produced by infusion with 1.1 M lactic acid) significantly lowered blood flow (ml/min/100 g) to the full thickness wall of the jejunum from 135 ± 11 to 93 ± 14 and in the full thickness wall of the ileum from 122 ± 13 to 95 ± 11. The decrease was mainly due to the decline in blood flow to mucosa of the segment, where flow decreased from 182 ± 20 to 83 ± 14 in the jejunum and from 130 ± 10 to 107 ± 9 in the ileum. Fetal hypoxemia (PaO2 of 14.9 mm Hg; induced by allowing ewes to breath 11.1% O2 and 88.9 % nitrogen) reduced blood flow only to the jejunal mucosa from 142 ± 14 to 99 ± 16. The reduction in blood flow to the full thickness wall of the jejunum and the ileum did not change significantly from the control period, when PaO2 was 25 mm Hg.
Details
- Title: Subtitle
- Effect of acidosis and hypoxia on intestinal blood flow of sheep fetus
- Creators
- M. K Younoszai - University of IowaT Kisker - University of IowaJ Robillard - University of IowaR Nathan - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Biology of the neonate, Vol.49(1), pp.29-35
- Publisher
- Karger
- DOI
- 10.1159/000242506
- PMID
- 3947690
- ISSN
- 0006-3126
- eISSN
- 1421-9727
- Number of pages
- 7
- Language
- English
- Date published
- 1986
- Academic Unit
- Molecular Physiology and Biophysics; Nephrology, Dialysis and Transplantation; Stead Family Department of Pediatrics; Medicine Administration
- Record Identifier
- 9984774210402771
Metrics
1 Record Views