Effect of chlorpromazine on drug absorption and gastric emptying in man

Oscar Ulf Petring; Benny Adelhøj; Merete Ibsen; Henrik Enghusen Poulsen

doi:10.1007/BF03010511

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Effect of chlorpromazine on drug absorption and gastric emptying in man

Journal article

Open access

Peer reviewed

Effect of chlorpromazine on drug absorption and gastric emptying in man

Oscar Ulf Petring, Benny Adelhøj, Merete Ibsen and Henrik Enghusen Poulsen

Canadian journal of anesthesia, Vol.34(6), pp.563-565

11/1987

DOI: 10.1007/BF03010511

PMID: 3677280

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Abstract

In a double-blind study the effect of a single IV dose (25 mg) of chlorpromazine on gastric emptying, as determined by the rate of paracetamol absorption, was measured in seven healthy volunteers. Each volunteer acted as his/her own control. There was no significant difference between the maximum paracetamol concentration, the time to reach the plasma maximum concentration, and the area under the plasma concentration time curve from 0-120 minutes on the two occasions, indicating unchanged gastric emptying after administration of chlorpromazine.

Details

Title: Subtitle: Effect of chlorpromazine on drug absorption and gastric emptying in man
Creators: Oscar Ulf Petring
Benny Adelhøj
Merete Ibsen
Henrik Enghusen Poulsen
Resource Type: Journal article
Publication Details: Canadian journal of anesthesia, Vol.34(6), pp.563-565
DOI: 10.1007/BF03010511
PMID: 3677280
NLM abbreviation: Can J Anaesth
ISSN: 0832-610X
eISSN: 1496-8975
Language: English
Date published: 11/1987
Academic Unit: Anesthesia
Record Identifier: 9984006345302771

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