Journal article
Effect of internal limiting membrane abrasion on retinal tissues in macular holes
Investigative ophthalmology & visual science, Vol.56(5), pp.2783-2789
05/2015
DOI: 10.1167/iovs.14-16355
PMCID: PMC4416746
PMID: 26024069
Abstract
The purpose of this study was to identify the structural and histological effects of a Tano diamond-dusted membrane scraper (DDMS) on the retinal surface after internal limiting membrane (ILM) abrasion in macular hole surgery. Institutional experimental study was performed in 11 eyes. All eyes underwent ILM abrasion in the operating room with a DDMS for macular hole repair as an alternative to traditional ILM peeling. Three human donor eyes underwent an identical procedure in the laboratory. Retinal tissues were removed by ILM abrasion with a DDMS during vitrectomy for macular hole repair and retinal tissues remaining in human donor eyes. Main outcome measures were microscopic and immunohistological characteristics of instrument tip tissues and retinal structure after ILM abrasion. The tips of the Tano DDMS showed evidence of cellular membranes and ILM removal. The retinas showed distinct areas of lamellar ILM removal without penetration of the retinal nerve fiber layer (RNFL). Application of the Tano DDMS instrument is sufficient to remove membranes from the surface of the ILM and layers of the ILM without disruption of the underlying RNFL. Internal limiting membrane abrasion can be a useful and effective alternative to complete ILM removal for macular surgery.
Details
- Title: Subtitle
- Effect of internal limiting membrane abrasion on retinal tissues in macular holes
- Creators
- David R P Almeida - Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United StatesEric K Chin - Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United StatesRyan M Tarantola - Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United StatesJames C Folk - Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United StatesH Culver Boldt - Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United StatesJessica M Skeie - Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States 2Omics Laboratory, Iowa City, Iowa, United StatesRobert F Mullins - Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United StatesStephen R Russell - Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United StatesVinit B Mahajan - Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States 2Omics Laboratory, Iowa City, Iowa, United States
- Resource Type
- Journal article
- Publication Details
- Investigative ophthalmology & visual science, Vol.56(5), pp.2783-2789
- Publisher
- United States
- DOI
- 10.1167/iovs.14-16355
- PMID
- 26024069
- PMCID
- PMC4416746
- ISSN
- 0146-0404
- eISSN
- 1552-5783
- Grant note
- K08EY020530 / NEI NIH HHS K08 EY020530 / NEI NIH HHS
- Language
- English
- Date published
- 05/2015
- Academic Unit
- Stead Family Department of Pediatrics; Ophthalmology and Visual Sciences
- Record Identifier
- 9983980053202771
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