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Effect of internal mammary vessels radiation dose on outcomes of free flap breast reconstruction
Journal article   Open access   Peer reviewed

Effect of internal mammary vessels radiation dose on outcomes of free flap breast reconstruction

Orit Kaidar-Person, Michael J. Eblan, Joseph M. Caster, Amita R. Shah, David Fried, Lawrence B. Marks, Clara N. Lee and Ellen L. Jones
The breast journal, Vol.25(2), pp.286-289
03/01/2019
DOI: 10.1111/tbj.13202
PMID: 30734417
url
https://doi.org/10.1111/tbj.13202View
Published (Version of record) Open Access

Abstract

To assess the impact of internal mammary (IM) vessels radiation dose on autologous free-flap based breast reconstruction outcomes. We retrospectively evaluated the medical records of breast cancer patients who underwent mastectomy and free-flap breast reconstruction after postoperative radiation therapy (RT) to the breast/chest wall with (n = 9) or without (n = 11) electively including the IM lymph nodes. Twenty patients were included. Median age at diagnosis was 50 years (range, 33-63). The median time interval between the start of RT and reconstructive surgery was 16 months (range, 6-45). The maximal IM vessels dose was not associated with the risk of all complications (P = 0.44) or fat necrosis (P = 0.31). The mean IM vessels dose was not significant for the risk of all complications (P = 0.13) but was significant for fat necrosis (P = 0.04). A high mean IM vessels dose was related to the occurrence of fat necrosis.
Life Sciences & Biomedicine Obstetrics & Gynecology Oncology Science & Technology

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