Journal article
Effect of porosity on the fluid flow characteristics and mechanical properties of tantalum scaffolds
Journal of biomedical materials research. Part B, Applied biomaterials, Vol.73(2), pp.315-324
05/2005
DOI: 10.1002/jbm.b.30229
PMID: 15736288
Abstract
In many cases of traumatic bone injury, bone grafting is required. The primary source of graft material is either autograft or allograft. The use of both material sources are well established, however, both suffer limitations. In response, many grafting alternatives are being explored. This article specifically focuses on a porous tantalum metal grafting material (Trabecular Metaltrade mark) marketed by Zimmer. Twenty-one cylindrical scaffolds were manufactured (66% to 88% porous) and tested for porosity, intrinsic permeability, tangent elastic modulus, and for yield stress and strain behavior. Scaffold microstructural geometries were also measured. Tantalum scaffold intrinsic permeability ranged from 2.1 x 10(-10) to 4.8 x 10(-10) m(2) and tangent elastic modulus ranged from 373 MPa to 2.2 GPa. Both intrinsic permeability and tangent elastic modulus closely matched porosity-matched cancellous bone specimens from a variety of species and anatomic locations. Scaffold yield stress ranged from 4 to 12.7 MPa and was comparable to bovine and human cancellous bone. Yield strain was unaffected by scaffold porosity (average = 0.010 mm/mm). Understanding these structure-function relationships will help complete the basic physical characterization of this new material and will aid in the development of realistic mathematical models, ultimately enhancing future implant designs utilizing this material.
Details
- Title: Subtitle
- Effect of porosity on the fluid flow characteristics and mechanical properties of tantalum scaffolds
- Creators
- Daniel A Shimko - Department of Biomedical Engineering, Tulane University, New Orleans, Louisiana, USAValerie Franz ShimkoEdward A SanderKyle F DicksonEric A Nauman
- Resource Type
- Journal article
- Publication Details
- Journal of biomedical materials research. Part B, Applied biomaterials, Vol.73(2), pp.315-324
- DOI
- 10.1002/jbm.b.30229
- PMID
- 15736288
- NLM abbreviation
- J Biomed Mater Res B Appl Biomater
- ISSN
- 1552-4973
- eISSN
- 1552-4981
- Publisher
- United States
- Language
- English
- Date published
- 05/2005
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Orthopedics and Rehabilitation; Craniofacial Anomalies Research Center; Chemical and Biochemical Engineering
- Record Identifier
- 9984064583102771
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