Effectiveness of anidulafungin in eradicating Candida species in invasive candidiasis

M A Pfaller; D J Diekema; L Boyken; S A Messer; S Tendolkar; R J Hollis; B P Goldstein

doi:10.1128/AAC.49.11.4795-4797.2005

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Effectiveness of anidulafungin in eradicating Candida species in invasive candidiasis

Journal article

Open access

Peer reviewed

Effectiveness of anidulafungin in eradicating Candida species in invasive candidiasis

M A Pfaller, D J Diekema, L Boyken, S A Messer, S Tendolkar, R J Hollis and B P Goldstein

Antimicrobial agents and chemotherapy, Vol.49(11), pp.4795-4797

11/2005

DOI: 10.1128/AAC.49.11.4795-4797.2005

PMCID: PMC1280139

PMID: 16251335

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Abstract

In a phase 2 open-label, dose-ranging study in patients with candidemia, anidulafungin was effective in eradicating Candida albicans and other species of Candida. The anidulafungin MIC distribution showed that Candida albicans and C. glabrata were the most susceptible species and C. parapsilosis was the least susceptible species.

Microbial Sensitivity Tests

Candidiasis - drug therapy

Humans

Echinocandins

Peptides, Cyclic - therapeutic use

Adult

Candida - drug effects

Antifungal Agents - therapeutic use

Details

Title: Subtitle: Effectiveness of anidulafungin in eradicating Candida species in invasive candidiasis
Creators: M A Pfaller - Medical Microbiology Division, C606 GH, Department of Pathology, Roy J. and A. Carver College of Medicine, College of Public Health, University of Iowa, Iowa City, Iowa 52242, USA. michael-pfaller@uiowa.edu
D J Diekema
L Boyken
S A Messer
S Tendolkar
R J Hollis
B P Goldstein
Resource Type: Journal article
Publication Details: Antimicrobial agents and chemotherapy, Vol.49(11), pp.4795-4797
DOI: 10.1128/AAC.49.11.4795-4797.2005
PMID: 16251335
PMCID: PMC1280139
NLM abbreviation: Antimicrob Agents Chemother
ISSN: 0066-4804
eISSN: 1098-6596
Publisher: United States
Language: English
Date published: 11/2005
Academic Unit: Infectious Diseases; Epidemiology; Pathology; Internal Medicine
Record Identifier: 9983986364602771

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