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Effects of Abiraterone Acetate on Chronic Kidney Disease in 2 Patients With Metastatic Castration-resistant Prostate Cancer
Journal article   Open access   Peer reviewed

Effects of Abiraterone Acetate on Chronic Kidney Disease in 2 Patients With Metastatic Castration-resistant Prostate Cancer

Edoardo Francini, Roberto Petrioli, Anna Ida Fiaschi, Letizia Laera and Giandomenico Roviello
Medicine (Baltimore), Vol.93(27), pp.e163-e163
12/01/2014
DOI: 10.1097/MD.0000000000000163
PMID: 25501058
url
https://doi.org/10.1097/MD.0000000000000163View
Published (Version of record) Open Access

Abstract

Prostate cancer is the second leading cause of cancer-related death in men in most Western countries. In this report, we present 2 cases of metastatic castration-resistant prostate cancer and chronic kidney disease. Both patients underwent and developed clinical resistance to androgen-deprivation therapy. Subsequently, the patients were treated with the conventional chemotherapeutic approach, which resulted in the worsening of renal function and performance status. Therefore, we opted for treatment with abiraterone acetate, and the patients exhibited improvements in renal function with good response of the disease.
General & Internal Medicine Life Sciences & Biomedicine Medicine, General & Internal Science & Technology

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