Journal article
Effects of Early Nutritional Interventions on the Development of Atopic Disease in Infants and Children : The Role of Maternal Dietary Restriction, Breastfeeding, Timing of Introduction of Complementary Foods, and Hydrolyzed Formulas
Pediatrics (Evanston), Vol.121(1), pp.183-191
2008
DOI: 10.1542/peds.2007-3022
PMID: 18166574
Abstract
This clinical report reviews the nutritional options during pregnancy, lactation, and the first year of life that may affect the development of atopic disease (atopic dermatitis, asthma, food allergy) in early life. It replaces an earlier policy statement from the American Academy of Pediatrics that addressed the use of hypoallergenic infant formulas and included provisional recommendations for dietary management for the prevention of atopic disease. The documented benefits of nutritional intervention that may prevent or delay the onset of atopic disease are largely limited to infants at high risk of developing allergy (ie, infants with at least 1 first-degree relative [parent or sibling] with allergic disease). Current evidence does not support a major role for maternal dietary restrictions during pregnancy or lactation. There is evidence that breastfeeding for at least 4 months, compared with feeding formula made with intact cow milk protein, prevents or delays the occurrence of atopic dermatitis, cow milk allergy, and wheezing in early childhood. In studies of infants at high risk of atopy and who are not exclusively breastfed for 4 to 6 months, there is modest evidence that the onset of atopic disease may be delayed or prevented by the use of hydrolyzed formulas compared with formula made with intact cow milk protein, particularly for atopic dermatitis. Comparative studies of the various hydrolyzed formulas also indicate that not all formulas have the same protective benefit. There is also little evidence that delaying the timing of the introduction of complementary foods beyond 4 to 6 months of age prevents the occurrence of atopic disease. At present, there are insufficient data to document a protective effect of any dietary intervention beyond 4 to 6 months of age for the development of atopic disease. Copyright © 2008 by the American Academy of Pediatrics.
Details
- Title: Subtitle
- Effects of Early Nutritional Interventions on the Development of Atopic Disease in Infants and Children : The Role of Maternal Dietary Restriction, Breastfeeding, Timing of Introduction of Complementary Foods, and Hydrolyzed Formulas
- Creators
- Frank R Greer - United States Food and Drug AdministrationScott H Sicherer - United States Food and Drug AdministrationSue Ann Anderson - United States Food and Drug AdministrationDonna BLUM-KEMELOR - US Department of Agriculture, United StatesMargaret P Boland - Canadian Paediatric SocietyLaurence GRUMMER-STRAWN - Centers for Disease ControlCapt Van S Hubbard - National Institutes of HealthBenson M Silverman - United States Food and Drug AdministrationPaul V Williams - United States Food and Drug AdministrationMichael J Welch - United States Food and Drug AdministrationSami L Bahna - United States Food and Drug AdministrationBradley E Chipps - United States Food and Drug AdministrationA. Wesley Burks - United States Food and Drug AdministrationMary Beth Fasano - United States Food and Drug AdministrationMitchell R Lester - United States Food and Drug AdministrationFrank S Virant - United States Food and Drug AdministrationTodd A Mahr - American College of Allergy, Asthma and ImmunologyDennis R Ownby - United States Food and Drug AdministrationGary S Rachelefsky - American Academy of Allergy, Asthma and ImmunologyDebra Burrowes - United States Food and Drug AdministrationRobert D Baker - United States Food and Drug AdministrationJatinder J. S Bhatia - United States Food and Drug AdministrationStephen Robert Daniels - United States Food and Drug AdministrationMarcie B Schneider - United States Food and Drug AdministrationJanet Silverstein - United States Food and Drug AdministrationDan W Thomas - United States Food and Drug AdministrationCommittee on Nutrition and Section on Allergy and Immunology
- Resource Type
- Journal article
- Publication Details
- Pediatrics (Evanston), Vol.121(1), pp.183-191
- Publisher
- American Academy of Pediatrics
- DOI
- 10.1542/peds.2007-3022
- PMID
- 18166574
- ISSN
- 0031-4005
- eISSN
- 1098-4275
- Language
- English
- Date published
- 2008
- Academic Unit
- Stead Family Department of Pediatrics; Rheumatology, Allergy, and Immunology; Immunology; Internal Medicine
- Record Identifier
- 9984354117602771
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