Journal article
Effects of Frequent Hemodialysis on Perceived Caregiver Burden in the Frequent Hemodialysis Network Trials
Clinical journal of the American Society of Nephrology, Vol.9(5), pp.936-942
05/07/2014
DOI: 10.2215/CJN.07170713
PMCID: PMC4011443
PMID: 24721892
Abstract
Background and objectivesPatients receiving hemodialysis often perceive their caregivers are overburdened. We hypothesize that increasing hemodialysis frequency would result in higher patient perceptions of burden on their unpaid caregivers.Design, setting, participants, & measurementsIn two separate trials, 245 patients were randomized to receive in-center daily hemodialysis (6 days/week) or conventional hemodialysis (3 days/week) while 87 patients were randomized to receive home nocturnal hemodialysis (6 nights/week) or home conventional hemodialysis for 12 months. Changes in overall mean scores over time in the 10-question Cousineau perceived burden scale were compared.ResultsIn total, 173 of 245 (70%) and 80 of 87 (92%) randomized patients in the Daily and Nocturnal Trials, respectively, reported having an unpaid caregiver at baseline or during follow-up. Relative to in-center conventional dialysis, the 12-month change in mean perceived burden score with in-center daily hemodialysis was -2.1 (95% confidence interval, -9.4 to +5.3; P=0.58). Relative to home conventional dialysis, the 12-month change in mean perceived burden score with home nocturnal dialysis was +6.1 (95% confidence interval, -0.8 to +13.1; P=0.08). After multiple imputation for missing data in the Nocturnal Trial, the relative difference between home nocturnal and home conventional hemodialysis was +9.4 (95% confidence interval, +0.55 to +18.3; P=0.04). In the Nocturnal Trial, changes in perceived burden were inversely correlated with adherence to dialysis treatments (Pearson r=-0.35; P=0.02).ConclusionRelative to conventional hemodialysis, in-center daily hemodialysis did not result in higher perceptions of caregiver burden. There was a trend to higher perceived caregiver burden among patients randomized to home nocturnal hemodialysis. These findings may have implications for the adoption of and adherence to frequent nocturnal hemodialysis.
Details
- Title: Subtitle
- Effects of Frequent Hemodialysis on Perceived Caregiver Burden in the Frequent Hemodialysis Network Trials
- Creators
- Rita S. Suri - Material (Belgium)Brett Larive - Material (Belgium)Yoshio Hall - Material (Belgium)Paul L. Kimmel - Material (Belgium)Alan S. Kliger - Material (Belgium)Nathan Levin - Material (Belgium)Manjula Kurella Tamura - Material (Belgium)Glenn M. Chertow - Material (Belgium)Frequent Hemodialysis Network (FHN) Trial Group
- Contributors
- D Somers (Contributor) - University of Iowa, Internal Medicine
- Resource Type
- Journal article
- Publication Details
- Clinical journal of the American Society of Nephrology, Vol.9(5), pp.936-942
- DOI
- 10.2215/CJN.07170713
- PMID
- 24721892
- PMCID
- PMC4011443
- NLM abbreviation
- Clin J Am Soc Nephrol
- ISSN
- 1555-9041
- eISSN
- 1555-905X
- Publisher
- Amer Soc Nephrology
- Number of pages
- 7
- Grant note
- Fonds de recherche du Quebec Sante; Fonds de la Recherche en Sante du Quebec Dialysis Clinics Centers for Medicare and Medicaid Services Fresenius Medical Care National Institutes of Health Research Foundation National Institute of Diabetes and Digestive and Kidney Diseases; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) Amgen Baxter, Inc.
- Language
- English
- Date published
- 05/07/2014
- Academic Unit
- Nephrology; Internal Medicine
- Record Identifier
- 9984359800402771
Metrics
9 Record Views