Journal article
Effects of Prostatic Artery Embolization on the Dynamic Component of Benign Prostate Hyperplasia as Assessed by Ultrasound Elastography: A Pilot Series
Cardiovascular and interventional radiology, Vol.42(7), pp.1001-1007
07/01/2019
DOI: 10.1007/s00270-019-02220-x
PMID: 30993369
Abstract
PurposeTo determine the effects of prostatic artery embolization (PAE) on prostaticelasticity as assessed by Ultrasound Elastography (US-E), as well as to describe the feasibility and role of US-E as a novel tool in both pre- and post-PAE evaluation.Materials and MethodsThis is a prospective, single-center investigation that included eight patients undergoing PAE for treatment of lower urinary tract symptoms (LUTS) attributed to benign prostate hyperplasia (BPH). Baseline and 3-month follow-up evaluations were performed and included prostate-specific antigen (PSA), uroflowmetry, pelvic magnetic resonance imaging and clinical assessment using the International Prostate Symptom Score (IPSS) questionnaire and the IPSS-Quality of life (QoL) item. US-E with measurement of the prostatic Elastic Modulus (EM) was performed before PAE and at 1-month follow-up.ResultsAfter PAE, US-E showed a significant reduction of prostatic EM as assessed in kPa (33.14 vs. 47.24, -29.8%, p=0.002) and in m/s (3.75 vs. 4.63, -19.0%, p<0.001). Also, the transitional/peripheral zone ratio was significantly reduced by 45.36% (0.53 vs. 0.97, p<0.05). All eight patients presented with significant LUTS improvement after PAE (p<0.05 for IPSS, QoL, prostate volume, peak urinary flow rate and PSA).ConclusionsFindings described in this study suggest that PAE significantly reduces prostaticEM, leading to a positive effect on BPH dynamic component related to prostatic elasticity. Also, it features US-E as an additional tool for pre- and post-PAE evaluation, describing a novel indication for this technology.
Details
- Title: Subtitle
- Effects of Prostatic Artery Embolization on the Dynamic Component of Benign Prostate Hyperplasia as Assessed by Ultrasound Elastography: A Pilot Series
- Creators
- Andre Moreira de Assis - Universidade de São PauloAirton Mota Moreira - Universidade de São PauloFrancisco Cesar Carnevale - Universidade de São PauloAntonio Sergio Zafred Marcelino - Sirio Libanes Hosp, Radiol Dept, Adma Jafet St,115, BR-01308050 Sao Paulo, SP, BrazilLuciana Mendes de Oliveira Cerri - Hospital Sírio-LibanêsAlberto Azoubel Antunes - Universidade de São PauloMiguel Srougi - Universidade de São PauloGiovanni Guido Cerri - Hospital Sírio-Libanês
- Resource Type
- Journal article
- Publication Details
- Cardiovascular and interventional radiology, Vol.42(7), pp.1001-1007
- Publisher
- Springer Nature
- DOI
- 10.1007/s00270-019-02220-x
- PMID
- 30993369
- ISSN
- 0174-1551
- eISSN
- 1432-086X
- Number of pages
- 7
- Language
- English
- Date published
- 07/01/2019
- Academic Unit
- Radiology
- Record Identifier
- 9984697722102771
Metrics
6 Record Views