Effects of age on responsiveness to adjunct hypnotic analgesia during invasive medical procedures

Susan K Lutgendorf; Elvira V Lang; Kevin S Berbaum; Daniel Russell; Michael L Berbaum; Henrietta Logan; Eric G Benotsch; Sebastian Schulz-Stubner; Derek Turesky; David Spiegel

doi:10.1097/PSY.0b013e31803133ea

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Effects of age on responsiveness to adjunct hypnotic analgesia during invasive medical procedures

Journal article

Peer reviewed

Effects of age on responsiveness to adjunct hypnotic analgesia during invasive medical procedures

Susan K Lutgendorf, Elvira V Lang, Kevin S Berbaum, Daniel Russell, Michael L Berbaum, Henrietta Logan, Eric G Benotsch, Sebastian Schulz-Stubner, Derek Turesky and David Spiegel

Psychosomatic medicine, Vol.69(2), pp.191-199

02/2007

DOI: 10.1097/PSY.0b013e31803133ea

PMID: 17289823

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Abstract

To assess the effects of age on responsiveness to self-hypnotic relaxation as an analgesic adjunct in patients undergoing invasive medical procedures. Secondary data analysis from a prospective trial with 241 patients randomized to receive hypnosis, attention, and standard care treatment during interventional radiological procedures. Growth curve analyses, hierarchical linear regressions, and logistic regressions using orthogonal contrasts were used for analysis. Outcome measures were Hypnotic Induction Profile scores, self-reported pain and anxiety, medication use, oxygen desaturation < or =89%, and procedure time. Hypnotizability did not vary with age (p = .19). Patients receiving attention and hypnosis had greater pain reduction during the procedure (p = .02), with trends toward lower pain with hypnosis (p = .07); this did not differ by age. As age increased, patients experienced more rapid pain control with hypnosis (p = .03). There was more rapid anxiety reduction with attention and hypnosis (p = .03). Trends toward lower final anxiety were also observed with attention and hypnosis versus standard care (p = .08), and with hypnosis versus attention (p = .059); these relationships did not differ by age. Patients requested and received less medication and had less oxygen desaturation < or =89% with attention and hypnosis (p < .001); this did not differ by age. However, as age increased, oxygen desaturation was greater in standard care (p = .03). Procedure time was reduced in the attention and hypnosis groups (p = .007); this did not vary by age. Older patients are hypnotizable and increasing age does not appear to mitigate the usefulness of hypnotic analgesia during invasive medical procedures.

Analgesics - therapeutic use

Prospective Studies

Age Factors

Pain - prevention & control

Humans

Middle Aged

Male

Radiography, Interventional - adverse effects

Pain - psychology

Aged, 80 and over

Pain - etiology

Adult

Female

Aged

Hypnosis

Details

Title: Subtitle: Effects of age on responsiveness to adjunct hypnotic analgesia during invasive medical procedures
Creators: Susan K Lutgendorf - Department of Psychology, University of Iowa, Iowa City, IA 52242, USA. susan-lutgendorf@uiowa.edu
Elvira V Lang
Kevin S Berbaum
Daniel Russell
Michael L Berbaum
Henrietta Logan
Eric G Benotsch
Sebastian Schulz-Stubner
Derek Turesky
David Spiegel
Resource Type: Journal article
Publication Details: Psychosomatic medicine, Vol.69(2), pp.191-199
DOI: 10.1097/PSY.0b013e31803133ea
PMID: 17289823
NLM abbreviation: Psychosom Med
ISSN: 0033-3174
eISSN: 1534-7796
Publisher: United States
Grant note: P20 AT-756 / NCCIH NIH HHS 1R01 AT 0002-05 / NCCIH NIH HHS R01 AT000002 / NCCIH NIH HHS R21 CA102515 / NCI NIH HHS K24 AT001074 / NCCIH NIH HHS 1K24 AT 01074-01 / NCCIH NIH HHS
Language: English
Date published: 02/2007
Academic Unit: Preventive and Community Dentistry; Radiology; Psychological and Brain Sciences; Iowa Neuroscience Institute; Obstetrics and Gynecology; Urology
Record Identifier: 9984065882602771

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