Journal article
Effects of angiographic contrast media on sino-atrial nodal function
Cardiovascular research, Vol.10(2), pp.214-223
03/1976
DOI: 10.1093/cvr/10.2.214
PMID: 7355
Abstract
Injection of meglumine diatrizoate (Renografin-76) into the selectively perfused sinus node artery of the dog produces bradycardia which is unaltered by autonomic blockade or by changes in sinus node artery pressure. Contrast agents and other hyperosmolar substances prolong the R-R interval in proportion to their osmolarity. Selective injection of contrast media into other cannulated segments of the coronary tree produces no change in heart rate. Transfemoral arteriography, however, produces bradycardia with both right and left coronary injections. Both direct and reflex sinus node depression occur with coronary arteriography in the dog. Direct effects are mediated by hyperosmolarity.
Details
- Title: Subtitle
- Effects of angiographic contrast media on sino-atrial nodal function
- Creators
- Carl W WhiteDwain L EckbergTohru InasakaFrancois M Abboud
- Resource Type
- Journal article
- Publication Details
- Cardiovascular research, Vol.10(2), pp.214-223
- Publisher
- England
- DOI
- 10.1093/cvr/10.2.214
- PMID
- 7355
- ISSN
- 0008-6363
- eISSN
- 1755-3245
- Language
- English
- Date published
- 03/1976
- Academic Unit
- Molecular Physiology and Biophysics; Cardiovascular Medicine; Fraternal Order of Eagles Diabetes Research Center; Internal Medicine
- Record Identifier
- 9984025424602771
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