Journal article
Effects of cardiac resynchronization therapy on health-related quality of life in older adults with heart failure
Clinical interventions in aging, Vol.3(3), pp.553-560
09/2008
DOI: 10.2147/CIA.S1823
PMCID: PMC2682384
PMID: 18982925
Abstract
The aim of the study was to examine changes in health-related quality of life among older adults undergoing cardiac resynchronization therapy (CRT), a pacemaker based intervention for heart failure. Twenty-one patients (mean age = 68; SD = 8) completed measures of cardiovascular health and quality of life prior to and 3-months post-CRT. Following the intervention, patients reported improvements in their perception of their physical functioning (t = 2.8,
p
< 0.01) and feelings of vitality (t = 2.9,
p
< 0.01) on the MOS SF-36 Health Survey. Patients improved on objective clinical measures of exercise capacity, cardiac ejection fraction, and ventricular dyssynchrony. Younger patients reported greater improvements in physical functioning and decreases in pain. Higher baseline body mass index was associated with less improvement in physical functioning. Finally, patients with nonischemic heart failure reported greater improvements on multiple subscales of the SF-36 than patients with ischemic heart failure. This preliminary study documented improvements in health-related quality of life following CRT. The findings highlight that specific patient characteristics may be associated with quality of life changes. Future studies will benefit from including quality of life measures that assess multiple health-related domains.
Details
- Title: Subtitle
- Effects of cardiac resynchronization therapy on health-related quality of life in older adults with heart failure
- Creators
- Karin F Hoth - Division of Psychosocial Medicine, National Jewish Medical and Research Center, Denver, CO, USAJustin Nash - Department of Psychiatry and Human BehaviorAthena Poppas - Department of Cardiology, Warren Alpert Medical School of Brown University, Providence, RI, USAKristin E Ellison - Department of Cardiology, Warren Alpert Medical School of Brown University, Providence, RI, USARobert H Paul - Department of Psychology, Division of Behavioral Neuroscience, University of Missouri St. Louis, St. Louis, MO, USARonald A Cohen - Department of Psychiatry and Human Behavior
- Resource Type
- Journal article
- Publication Details
- Clinical interventions in aging, Vol.3(3), pp.553-560
- DOI
- 10.2147/CIA.S1823
- PMID
- 18982925
- PMCID
- PMC2682384
- NLM abbreviation
- Clin Interv Aging
- ISSN
- 1176-9092
- eISSN
- 1178-1998
- Publisher
- Dove Medical Press
- Language
- English
- Date published
- 09/2008
- Academic Unit
- Psychiatry; Iowa Neuroscience Institute
- Record Identifier
- 9984066380302771
Metrics
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