Journal article
Effects of environmental warming on blood components dispensed in syringes for neonatal transfusions
The Journal of pediatrics, Vol.109(1), pp.109-113
1986
DOI: 10.1016/S0022-3476(86)80587-X
PMID: 3723229
Abstract
We examined the quality of blood components dispensed in syringes fortransfusion into neonates, including the effects on quality of environmental conditions to which blood is exposed when it is transfused into neonates nursed in warm-air incubators or under radiant warmers. Syringes of blood placed in incubators rapidly warmed to 36°C. Blood placed under radiant warmers operated at full power was heated rapidly to temperatures approaching 45°C, and all blood components exhibited evidence of falling pH and cellular damage after 6 hours exposure to radiant energy. Erythrocyte damage was suggested by an increase in plasma hemoglobin, potassium, and lactic dehydrogenase. Platelets lost the ability to recover from hypotonic shock. Granulocytes exhibited a marked defect in the ability to produce superoxide anion after stimulation. The excessive warming and functional abnormalities exhibited by all blood components exposed to infrared energy were abrogated when syringes were shielded by covering them with aluminum foll. The clinical importance of these experimental findings remains to be established. Meanwhile, it would seem prudent either to shield syringes of blood placed under radiant warmers by covering them with aluminum foil or to limit the volume of a single transfusion to a quantity that can be infused within a relatively brief period.
Details
- Title: Subtitle
- Effects of environmental warming on blood components dispensed in syringes for neonatal transfusions
- Creators
- Ronald G. Strauss - Gulf Coast Regional Blood CenterEdward F. Bell - Gulf Coast Regional Blood CenterEsther L. Snyder - Gulf Coast Regional Blood CenterChar Elbert - Gulf Coast Regional Blood CenterGreta Crawford - Gulf Coast Regional Blood CenterAlice Floss - Gulf Coast Regional Blood CenterPatricia K. Wilmoth - Gulf Coast Regional Blood CenterGladys R. Rios - Gulf Coast Regional Blood CenterFranklin P. Koontz - Gulf Coast Regional Blood Center
- Resource Type
- Journal article
- Publication Details
- The Journal of pediatrics, Vol.109(1), pp.109-113
- Publisher
- Mosby, Inc
- DOI
- 10.1016/S0022-3476(86)80587-X
- PMID
- 3723229
- ISSN
- 0022-3476
- eISSN
- 1097-6833
- Language
- English
- Date published
- 1986
- Academic Unit
- Stead Family Department of Pediatrics; Pathology; Neonatology
- Record Identifier
- 9984354118802771
Metrics
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