Journal article
Effects of frequent marijuana use on brain tissue volume and composition
Neuroreport, Vol.11(3), pp.491-496
02/28/2000
DOI: 10.1097/00001756-200002280-00013
PMID: 10718301
Abstract
To investigate CNS effects of frequent marijuana use, brain tissue volume and composition were measured using magnetic resonance imaging (MRI) in 18 current, frequent, young adult marijuana users and 13 comparable, non-using controls. Automated image analysis techniques were used to measure global and regional brain volumes, including, for most regions, separate measures of gray and white matter. The marijuana users showed no evidence of cerebral atrophy or global or regional changes in tissue volumes. Volumes of ventricular CSF were not higher in marijuana users than controls, but were, in fact, lower. There were no clinically significant abnormalities in any subjectʼs MRI. Sex differences were detected in several global volume measures.
Details
- Title: Subtitle
- Effects of frequent marijuana use on brain tissue volume and composition
- Creators
- Robert Block - 1Department of Anesthesia, Westlawn Building, Room 5140, Iowa City, IA 52242-1100 USA 2Department of Psychiatry, University of Iowa, Iowa City, IA 52242-1100 USA 3Department of Radiology, University of Iowa, Iowa City, IA 52242-1100 USA 4Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA 52242-1100 USA 5School of Social Work, University of Iowa, Iowa City, IA 52242-1100 USA 6Present Address: Alzheimerʼs Research Unit, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA 02129, USADaniel OʼLearyJames EhrhardtJean AugustinackM GhoneimStephan ArndtJames Hall
- Resource Type
- Journal article
- Publication Details
- Neuroreport, Vol.11(3), pp.491-496
- DOI
- 10.1097/00001756-200002280-00013
- PMID
- 10718301
- NLM abbreviation
- Neuroreport
- ISSN
- 0959-4965
- eISSN
- 1473-558X
- Publisher
- Lippincott Williams & Wilkins, Inc
- Language
- English
- Date published
- 02/28/2000
- Academic Unit
- Radiology; Psychiatry; Iowa Neuroscience Institute; Biostatistics; Nursing; Anesthesia; Injury Prevention Research Center
- Record Identifier
- 9984004188902771
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