Journal article
Effects of furosemide on body water compartments in infants with bronchopulmonary dysplasia
Pediatric research, Vol.26(2), pp.121-124
08/1989
DOI: 10.1203/00006450-198908000-00010
PMID: 2771518
Abstract
We studied the effects of a single dose of intravenous furosemide on the body water compartments of nine infants with bronchopulmonary dysplasia. We measured total body water, extracellular water, and plasma volume using deuterium oxide, sodium bromide, and Evans blue dye, respectively. From the results of these measurements, we calculated cell water, interstitial water, red cell volume, and total blood volume. We performed these measurements on the first day of the study and again 28 h later, 4 h after an intravenous dose of furosemide (1 mg/kg). All infants had a brisk diuresis in the first hour after the dose, but urine output was no greater during the 24-h period after the dose than during the preceding 24-h period. Total body water, extracellular water, and interstitial water were significantly decreased 4 h after furosemide. There was no change in plasma volume, red cell volume, or total blood volume.
Details
- Title: Subtitle
- Effects of furosemide on body water compartments in infants with bronchopulmonary dysplasia
- Creators
- B Helen O'Donovan - Department of Pediatrics, University of Iowa, Iowa City 52242Edward F Bell - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Pediatric research, Vol.26(2), pp.121-124
- DOI
- 10.1203/00006450-198908000-00010
- PMID
- 2771518
- ISSN
- 0031-3998
- eISSN
- 1530-0447
- Grant note
- HD07578 / NICHD NIH HHS RR00059 / NCRR NIH HHS HD16974 / NICHD NIH HHS
- Language
- English
- Date published
- 08/1989
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology
- Record Identifier
- 9984093326002771
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