Journal article
Effects of pulsed electromagnetic field stimulation on distraction osteogenesis in the rabbit tibial leg lengthening model
Journal of pediatric orthopaedics, Vol.23(4), pp.478-483
2003
DOI: 10.1097/01241398-200307000-00012
PMID: 12826946
Abstract
The purpose of this study was to determine whether exposure to pulsed electromagnetic field (PEMF) would shorten the healing time of regenerate bone in a rabbit tibial distraction model. Beginning 1 day after surgery, mid-shaft tibial osteotomies, stabilized with external fixators, were distracted 0.25 mm twice daily for 21 days and received either no exposure (sham control) or 1 hour per day exposure to low-amplitude, low-frequency PEMF. Tibiae were tested for torsional strength after 9, 16, and 23 days post-distraction. PEMF-treated tibiae were significantly stronger than shams at all three time points. By 16 days post-distraction, the PEMF group had achieved biomechanical strength essentially equivalent to intact bone. Shams did not achieve normal biomechanical strength even after 23 days post-distraction. In this tibial distraction model, short daily PEMF exposures accelerated consolidation of regenerate bone. Clinical usefulness awaits testing.
Details
- Title: Subtitle
- Effects of pulsed electromagnetic field stimulation on distraction osteogenesis in the rabbit tibial leg lengthening model
- Creators
- Douglas C FREDERICKS - Bone Healing Research Laboratory, University of Iowa College of Medicine, Iowa City, Iowa, United StatesDebra J PIEHL - Bone Healing Research Laboratory, University of Iowa College of Medicine, Iowa City, Iowa, United StatesJoy T BAKER - Bone Healing Research Laboratory, University of Iowa College of Medicine, Iowa City, Iowa, United StatesJoan ABBOTT - Bone Healing Research Laboratory, University of Iowa College of Medicine, Iowa City, Iowa, United StatesJames V NEPOLA - Bone Healing Research Laboratory, University of Iowa College of Medicine, Iowa City, Iowa, United States
- Resource Type
- Journal article
- Publication Details
- Journal of pediatric orthopaedics, Vol.23(4), pp.478-483
- DOI
- 10.1097/01241398-200307000-00012
- PMID
- 12826946
- NLM abbreviation
- J Pediatr Orthop
- ISSN
- 0271-6798
- eISSN
- 1539-2570
- Publisher
- Lippincott; Hagerstown, MD
- Language
- English
- Date published
- 2003
- Academic Unit
- Orthopedics and Rehabilitation; Craniofacial Anomalies Research Center
- Record Identifier
- 9984040562802771
Metrics
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