Effects of weight loss on the course of idiopathic intracranial hypertension in women

M J Kupersmith; L Gamell; R Turbin; V Peck; P Spiegel; M Wall

doi:10.1212/wnl.50.4.1094

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Effects of weight loss on the course of idiopathic intracranial hypertension in women

Journal article

Peer reviewed

Effects of weight loss on the course of idiopathic intracranial hypertension in women

M J Kupersmith, L Gamell, R Turbin, V Peck, P Spiegel and M Wall

Neurology, Vol.50(4), pp.1094-1098

04/1998

DOI: 10.1212/wnl.50.4.1094

PMID: 9566400

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Abstract

To determine the role of weight loss in the treatment of idiopathic intracranial hypertension (IIH) in obese women. Chart review of 250 patients with suspected IIH revealed 58 women who met our criteria, did not undergo early surgical intervention, and had adequate documentation of visual status, papilledema, and weight at the baseline evaluation and at 6 months or longer. Patients were divided into two groups based on whether weight loss > or = 2.5 kg occurred during any 3-month interval. Papilledema grade, visual acuity, and visual field grade at 6 months or longer and the time to improve each were recorded. Mean time in months to improve one grade for papilledema and visual field in one eye was 4.0 versus 6.7 (p = 0.013) and 4.6 versus 12.2 (p = 0.032), respectively, for the 38 patients with weight loss compared with the 20 patients with no weight loss. Papilledema resolved in 28/38 with weight loss (mean, 7.6 months) and 8/20 without weight loss (mean, 10.2 months; p = 0.352). There were no differences in final visual acuity or visual field between the two groups, but the papilledema grade was slightly better in the worst eye in each patient at baseline in the weight loss group (p = 0.03). Weight reduction is associated with more rapid recovery of both papilledema and visual field dysfunction in patients with IIH compared with those who do not lose weight.

Obesity - diet therapy

Obesity - complications

Humans

Middle Aged

Treatment Outcome

Vision, Low - diagnosis

Visual Acuity

Vision, Low - etiology

Papilledema

Visual Fields

Weight Loss

Intracranial Hypertension - surgery

Adolescent

Vision, Low - diet therapy

Adult

Female

Intracranial Hypertension - complications

Intracranial Hypertension - diet therapy

Details

Title: Subtitle: Effects of weight loss on the course of idiopathic intracranial hypertension in women
Creators: M J Kupersmith - Beth Israel Medical Center, New York Eye and Ear Infirmary, New York 10128, USA
L Gamell
R Turbin
V Peck
P Spiegel
M Wall
Resource Type: Journal article
Publication Details: Neurology, Vol.50(4), pp.1094-1098
Publisher: United States
DOI: 10.1212/wnl.50.4.1094
PMID: 9566400
ISSN: 0028-3878
eISSN: 1526-632X
Language: English
Date published: 04/1998
Academic Unit: Neurology; Ophthalmology and Visual Sciences
Record Identifier: 9983979988402771

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151 Times Cited - Web of Science