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Eicosanoids as Therapeutic Targets in Asthma
Journal article   Peer reviewed

Eicosanoids as Therapeutic Targets in Asthma

P Rastogi and J McHowat
Letters in drug design & discovery, Vol.3(9), pp.668-674
11/01/2006
DOI: 10.2174/157018006778341165

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Abstract

Asthma is a chronic inflammatory disease of the airways associated with variable airflow obstruction and increased responsiveness to a variety of stimuli. Arachidonic acid metabolites play an important role in the pathophysiology of asthma and in this review we examine the major products of the lipoxygenase and cycloxygenase pathways, their effects on the airways and the current strategies used to target them. © 2006 Bentham Science Publishers Ltd.

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