Elderly hypertensives show decreased cognitive performance compared with elderly normotensives

Juliana Magalhães Duarte Matoso; Wellington Bruno Santos; Irene de Freitas Henriques Moreira; Roberto Alves Lourenço; Marcelo Lima de Gusmão Correia

doi:10.5935/abc.20130080

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Elderly hypertensives show decreased cognitive performance compared with elderly normotensives

Journal article

Open access

Elderly hypertensives show decreased cognitive performance compared with elderly normotensives

Juliana Magalhães Duarte Matoso, Wellington Bruno Santos, Irene de Freitas Henriques Moreira, Roberto Alves Lourenço and Marcelo Lima de Gusmão Correia

Arquivos brasileiros de cardiologia, Vol.100(5), pp.444-451

05/2013

DOI: 10.5935/abc.20130080

PMID: 23579624

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Abstract

Essential hypertension has been associated with decreased cognitive performance; however, the literature is conflicting. This study aims at comparing cognitive performance between elderly normotensives ("N"; n = 17; age 68 ± 1; blood pressure = 133 ± 3/74 ±2 mmHg) and hypertensives ("H"; n = 28; age 69 ± 1, blood pressure = 148 ± 4/80 ± 1mmHg) with at least 5 years of education. The comprehensive neuropsychological assessment was comprised of the Cambridge Cognition-Revised (CAMCOG-R), the Trail Making Test A and B (TMT A and B) and the Rey Auditory Verbal Learning Test (RAVLT). Elderly hypertensives presented lower CAMCOG-R global scores (N = 87.6 ± 1.8; H = 78.6 ± 1.4; p = 0.002). The hypertensive's performance was slower in the TMT A and B (TMT A: N = 39 ± 3s; H = 57 ± 3s; p = 0.001; TMT B: N = 93 ± 7s; H = 124 ± 7s; p = 0.006), which was also reflected in smaller percentiles achieved by hypertensives in these tests. Hypertensive subjects exhibited a significantly lower RAVLT summation score (N = 51.8 ± 1.7; H = 40.7 ± 1.5; p < 0.0001). Even when adjusted for age, sex, education and depression symptoms, hypertension was an independent predictor of cognitive performance as measured by CAMCOG-R global score, TMT A and RAVLT summation score. Cognitive performance is lower in elderly hypertensives as compared with elderly normotensives.

Neuropsychological Tests

Epidemiologic Methods

Hypertension - psychology

Humans

Cognition - physiology

Female

Male

Aged

Blood Pressure - physiology

Hypertension - physiopathology

Details

Title: Subtitle: Elderly hypertensives show decreased cognitive performance compared with elderly normotensives
Creators: Juliana Magalhães Duarte Matoso - Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ – Brazil. juduartte@yahoo.com.br
Wellington Bruno Santos
Irene de Freitas Henriques Moreira
Roberto Alves Lourenço
Marcelo Lima de Gusmão Correia
Resource Type: Journal article
Publication Details: Arquivos brasileiros de cardiologia, Vol.100(5), pp.444-451
DOI: 10.5935/abc.20130080
PMID: 23579624
NLM abbreviation: Arq Bras Cardiol
ISSN: 0066-782X
eISSN: 1678-4170
Language: English
Date published: 05/2013
Academic Unit: Endocrinology and Metabolism; Internal Medicine
Record Identifier: 9984094384202771

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