Journal article
Elective single embryo transfer trends and predictors of a good perinatal outcome-United States, 1999 to 2010
Fertility and sterility, Vol.99(7), pp.1937-1943
06/01/2013
DOI: 10.1016/j.fertnstert.2013.01.134
PMCID: PMC4603751
PMID: 23453121
Abstract
Objective: To assess trends in elective single ET and identify factors associated with a good perinatal outcome.
Design: Retrospective cohort study.
Setting: Clinic-based data.
Patient(s): A total of 886,686 fresh, nondonor cycles reported to the National Assisted Reproductive Technology Surveillance System during 1999-2010, of which 17,166 met criteria for elective single ET.
Intervention(s): None.
Main Outcome Measure(s): Rates of elective single ET and good perinatal outcome (term, singleton infant with normal birth weight).
Result(s): In 2010, elective single ET comprised 5.6% of all fresh transfers, representing an eightfold increase since publication of first guidelines in 2004 recommending elective single ET. Compared with other ETs, elective single ETs were nearly twice as likely to result in a good perinatal outcome (37.1% vs. 18.9%, respectively). Among women using elective single ET, those aged <35 and 35-37 years had a good perinatal outcome (40.2% and 32.5%, respectively). In multivariable, log-binomial analyses, factors positively associated with a good perinatal outcome included male factor infertility, day 5 ET, and having >= 3 supernumerary embryos for cryopreservation.
Conclusion(s): Between 1999 and 2010, national rates of elective single ET increased. Given the frequency of good perinatal outcomes among women aged 35-37 years, guidelines for elective single ET could be expanded to include patients in this age group with favorable prognoses. 43. (C)2013 by American Society for Reproductive Medicine.
Details
- Title: Subtitle
- Elective single embryo transfer trends and predictors of a good perinatal outcome-United States, 1999 to 2010
- Creators
- Marissa L. Steinberg - Emory UniversitySheree Boulet - National Center for Chronic Disease Prevention and Health PromotionDmitry Kissin - Centers for Disease Control and PreventionLee Warner - National Center for Chronic Disease Prevention and Health PromotionDenise J. Jamieson - National Center for Chronic Disease Prevention and Health Promotion
- Resource Type
- Journal article
- Publication Details
- Fertility and sterility, Vol.99(7), pp.1937-1943
- Publisher
- Elsevier
- DOI
- 10.1016/j.fertnstert.2013.01.134
- PMID
- 23453121
- PMCID
- PMC4603751
- ISSN
- 0015-0282
- eISSN
- 1556-5653
- Number of pages
- 7
- Grant note
- CC999999 / Intramural CDC HHS
- Language
- English
- Date published
- 06/01/2013
- Academic Unit
- Obstetrics and Gynecology; VPMA - Administration
- Record Identifier
- 9984446405702771
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