Journal article
Electronic Cigarette Use in US Adults at Risk for or with COPD: Analysis from Two Observational Cohorts
Journal of general internal medicine : JGIM, Vol.32(12), pp.1315-1322
12/2017
DOI: 10.1007/s11606-017-4150-7
PMCID: PMC5698219
PMID: 28884423
Abstract
Electronic cigarettes (e-cigarettes) are battery-operated nicotine-delivery devices used by some smokers as a cessation tool as well as by never smokers.
To determine the usage of e-cigarettes in older adults at risk for or with chronic obstructive pulmonary disease (COPD).
Prospective cohorts.
COPDGene (N = 3536) and SPIROMICS (N = 1060) subjects who were current or former smokers aged 45-80.
Participants were surveyed to determine whether e-cigarette use was associated with longitudinal changes in COPD progression or smoking habits.
From 2010 to 2016, participants who had ever used e-cigarettes steadily increased to 12-16%, but from 2014 to 2016 current use was stable at ~5%. E-cigarette use in African-Americans (AA) and whites was similar; however, AA were 1.8-2.9 times as likely to use menthol-flavored e-cigarettes. Current e-cigarette and conventional cigarette users had higher nicotine dependence and consumed more nicotine than those who smoked only conventional cigarettes. E-cigarette users had a heavier conventional cigarette smoking history and worse respiratory health, were less likely to reduce or quit conventional cigarette smoking, had higher nicotine dependence, and were more likely to report chronic bronchitis and exacerbations. Ever e-cigarette users had more rapid decline in lung function, but this trend did not persist after adjustment for persistent conventional cigarette smoking.
E-cigarette use, which is common in adults with or at risk for COPD, was associated with worse pulmonary-related health outcomes, but not with cessation of smoking conventional cigarettes. Although this was an observational study, we find no evidence supporting the use of e-cigarettes as a harm reduction strategy among current smokers with or at risk for COPD.
Details
- Title: Subtitle
- Electronic Cigarette Use in US Adults at Risk for or with COPD: Analysis from Two Observational Cohorts
- Creators
- Russell P Bowler - National Jewish Health, 1400 Jackson Street, Denver, CO, 80206, USA. BowlerR@NJHealth.orgNadia N Hansel - Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USASean Jacobson - National Jewish Health, 1400 Jackson Street, Denver, CO, 80206, USAR Graham Barr - Departments of Medicine and Epidemiology, Columbia University Medical Center, New York, NY, USABarry J Make - National Jewish Health, 1400 Jackson Street, Denver, CO, 80206, USAMeiLan K Han - VA Ann Arbor Healthcare System, Ann Arbor, MI, USAWanda K O'Neal - Department of Medicine, Marsico Lung Institute/Cystic Fibrosis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USAElizabeth C Oelsner - Departments of Medicine and Epidemiology, Columbia University Medical Center, New York, NY, USARichard Casaburi - Rehabilitation Clinical Trials Center, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USAIgor Barjaktarevic - Division of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, California, Los Angeles, USAChris Cooper - Division of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, California, Los Angeles, USAMarilyn Foreman - Department of Medicine, Morehouse School of Medicine, Atlanta, GA, USARobert A Wise - Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USADawn L DeMeo - Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USAEdwin K Silverman - Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USAWilliam Bailey - Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USAKathleen F Harrington - Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USAPrescott G Woodruff - Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine and Cardiovascular Research Institute, University of California San Francisco, School of Medicine, San Francisco, CA, USAM Bradley Drummond - Department of Medicine, Marsico Lung Institute/Cystic Fibrosis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USACOPDGene InvestigatorsSPIROMICS Investigators
- Contributors
- Eric A Hoffman (Contributor) - University of Iowa, Radiology
- Resource Type
- Journal article
- Publication Details
- Journal of general internal medicine : JGIM, Vol.32(12), pp.1315-1322
- Publisher
- United States
- DOI
- 10.1007/s11606-017-4150-7
- PMID
- 28884423
- PMCID
- PMC5698219
- ISSN
- 0884-8734
- eISSN
- 1525-1497
- Grant note
- U01 HL089856 / NHLBI NIH HHS U01 HL089897 / NHLBI NIH HHS U01 HL137880 / NHLBI NIH HHS S10 OD018526 / NIH HHS K24 HL137013 / NHLBI NIH HHS K23 HL130627 / NHLBI NIH HHS
- Language
- English
- Date published
- 12/2017
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology; Internal Medicine
- Record Identifier
- 9984051559302771