Journal article
Embryo culture does not affect the longevity of offspring in mice
Reproduction (Cambridge, England), Vol.130(5), pp.599-601
11/2005
DOI: 10.1530/rep.1.00872
PMID: 16264090
Abstract
The oldest assisted reproductive technologies (ART)-conceived child is only 27 years old. Thus, the effects of ART on longevity are unknown, and it will be many years before this can be assessed in humans. We recently reported that culturing preimplantation mouse embryos under suboptimal conditions results in differences in how the offspring perform in behavioral assays that reflect anxiety (elevated zero maze) and spatial memory (Morris hidden water maze; Ecker et al. 2004). Here we monitored the mice generated in our previous study and found no difference in their longevity.
Details
- Title: Subtitle
- Embryo culture does not affect the longevity of offspring in mice
- Creators
- Joshua Sommovilla - Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USAWarren B BilkerTed AbelRichard M Schultz
- Resource Type
- Journal article
- Publication Details
- Reproduction (Cambridge, England), Vol.130(5), pp.599-601
- Publisher
- England
- DOI
- 10.1530/rep.1.00872
- PMID
- 16264090
- ISSN
- 1470-1626
- eISSN
- 1741-7899
- Grant note
- P50 MH 64045 / NIMH NIH HHS U01 HD 44575 / NICHD NIH HHS
- Language
- English
- Date published
- 11/2005
- Academic Unit
- Molecular Physiology and Biophysics; Psychiatry; Psychological and Brain Sciences; Iowa Neuroscience Institute; Neuroscience and Pharmacology; Biochemistry and Molecular Biology
- Record Identifier
- 9984065825302771
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