Journal article
Endobronchial valve treatment of persistent alveolopleural fistulae in a patient with cystic fibrosis and empyema
Journal of cystic fibrosis, Vol.19(5), pp.E36-E38
09/01/2020
DOI: 10.1016/j.jcf.2020.03.014
PMID: 32312675
Abstract
Persistent air leak (PAL) is a common problem after secondary pneumothorax due to cystic fibrosis (CF). These leaks, caused by either bronchopleural or alveolopleural fistula, are associated with higher morbidity and mortality [1]. Air leaks are traditionally treated with chronic chest tube drainage, chemical pleurodesis, or autologous blood patching in non-surgical candidates [1]. However, these strategies can increase infectious risk or pleural scarring, which are associated with poorer lung transplant surgical outcomes. Endobronchial valve (EBV) placement, while FDA-approved for use in both some surgical PALs and bronchoscopic volume reduction therapy, is one alternative option, but it could theoretically increase the risk of infection, especially in CF patients. Here, we report the case of a CF patient under evaluation for lung transplant who received EBVs for PAL after bilateral secondary spontaneous pneumothoraces. (C) 2020 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.
Details
- Title: Subtitle
- Endobronchial valve treatment of persistent alveolopleural fistulae in a patient with cystic fibrosis and empyema
- Creators
- Kale S. Bongers - University of Michigan–Ann ArborJose De Cardenas - University of Michigan–Ann Arbor
- Resource Type
- Journal article
- Publication Details
- Journal of cystic fibrosis, Vol.19(5), pp.E36-E38
- Publisher
- Elsevier
- DOI
- 10.1016/j.jcf.2020.03.014
- PMID
- 32312675
- ISSN
- 1569-1993
- eISSN
- 1873-5010
- Number of pages
- 3
- Grant note
- National Institutes of Health (NIH); United States Department of Health & Human Services; National Institutes of Health (NIH) - USA Wellcome Trust; European Commission
- Language
- English
- Date published
- 09/01/2020
- Academic Unit
- Internal Medicine
- Record Identifier
- 9984696755702771
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