Journal article
Endocrine Complications of Cystic Fibrosis: A Multisystem Disease of the Endocrine Organs
Seminars in respiratory and critical care medicine, Vol.40(6), pp.810-824
12/2019
DOI: 10.1055/s-0039-1697917
PMID: 31679155
Abstract
Abstract
Cystic fibrosis (CF) is one of the most common life-limiting genetic disorders. Although CF is typically considered primarily as a pulmonary disease, the CF conductance transmembrane regulator is present throughout the body. From an endocrine perspective, this multisystem disease manifests primarily in the pancreas as a unique form of diabetes (CF-related diabetes mellitus), as bone disease, and as reproductive health issues in people with CF. These complications have become ever more concerning to people with CF as treatment for pulmonary disease improves and lifespans lengthen, increasing the impact of nonpulmonary complications. Our understanding of the management of these concerns continues to evolve, and, although there are some effective treatments, there is great opportunity for continued investigation into the pathophysiology of the endocrine complications of CF and their treatment.
Details
- Title: Subtitle
- Endocrine Complications of Cystic Fibrosis: A Multisystem Disease of the Endocrine Organs
- Creators
- Katie Larson Ode - Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics, University of Iowa Stead Family Children's Hospital, Iowa City, IowaChristine L. Chan - Division of Pediatric Endocrinology, Department of Pediatrics, Colorado Children's Hospital, University of Colorado School of Medicine, Aurora, ColoradoAndrea Granandos - Division of Endocrinology and Metabolism, Department of Pediatrics, Children's Washington University School of Medicine in St. Louis, St. Louis, MissouriMelissa Putman - Massachusetts General HospitalAmir Moheet - University of Minnesota
- Resource Type
- Journal article
- Publication Details
- Seminars in respiratory and critical care medicine, Vol.40(6), pp.810-824
- Publisher
- Thieme Medical Publishers
- DOI
- 10.1055/s-0039-1697917
- PMID
- 31679155
- ISSN
- 1069-3424
- eISSN
- 1098-9048
- Language
- English
- Date published
- 12/2019
- Academic Unit
- Endocrinology and Diabetes; Stead Family Department of Pediatrics
- Record Identifier
- 9984354499802771
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