Journal article
Endometrial response to unopposed estrogens remains unaltered in patients with chronic renal failure receiving hemodialysis
Gynecologic and obstetric investigation, Vol.47(1), pp.26-28
01/01/1999
DOI: 10.1159/000010057
PMID: 9852388
Abstract
<p>Most patients with chronic renal failure who are on maintenance hemodialysis are anovulatory and have menstrual abnormalities. This study was designed to determine the prevalence of organic causes of abnormal uterine bleeding in this group of patients exposed to unopposed estrogens. Eighteen patients with chronic renal failure and abnormal uterine bleeding underwent vacuum curettage. The histopathologic findings were compared with a group of 154 premenopausal women who had abnormal uterine bleeding without detectable organic causes. Excluding patients with secretory and atrophic endometrium, only 2 of 8 patients (25%) with chronic renal failure had endometrial lesions while 44 of 131 patients (33.6%) had either endometrial polyp, simple or atypical endometrial hyperplasia or endometrial carcinoma (p > 0.05). The uremic environment caused by chronic renal failure does not alter the endometrial responsiveness to unopposed estrogens and may lead to the development of endometrial lesions.</p>
Details
- Title: Subtitle
- Endometrial response to unopposed estrogens remains unaltered in patients with chronic renal failure receiving hemodialysis
- Creators
- M. H. ErgeneliEyup Hakan Duran - University of IowaH. B. ZeynelogluB. DemirhanM. Erdogan
- Resource Type
- Journal article
- Publication Details
- Gynecologic and obstetric investigation, Vol.47(1), pp.26-28
- DOI
- 10.1159/000010057
- PMID
- 9852388
- ISSN
- 0378-7346
- Language
- English
- Date published
- 01/01/1999
- Academic Unit
- Obstetrics and Gynecology
- Record Identifier
- 9983557405202771
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